Tuberculosis

Question 1

initial drugs - 8 weeks

Answer 1

isoniazide, rifampicin, pyrazimide, ethambutol

Question 2

continuation phase- 18 weeks

Answer 2

isoniazide, rifampicin

Question 3

what is a side effect of tb drugs

Answer 3

hepatotoxicity

Question 4

what are the problems with current treatment

Answer 4

intolerance
side effects
length of therapy
number of tablets

Question 5

what increases the risk of resistance

Answer 5

high bacterial load
cavitations
HIV
incomplete treatment

Question 6

what is multiple drug resistant tuberculosis

Answer 6

resistant to rifampicin and isoniazid

leads to worse prognosis:
cavitations
empyaema
HIV

Question 7

what is secondary resistance

Answer 7

resistance in a case with previous chemo

Question 8

what is extremely drug resistant tb

Answer 8

fluroquinolone plus one of three injectable second line drugs

Question 9

how do you treat MDRTB

Answer 9

side room
negative pressure ventilation
masks for staff