Penicillins

Question 1

Methicillin, Oxacillin, Nafcillin, Cloxacillin, Dicloxacillin.

Answer 1

β-Lactamase-resistant Penicillins.

Question 2

Ampicillin & Amoxicillin.

Answer 2

Broad-spectrum penicillins

Question 3

Carbenicillin, Ticaracillin, Azlocillin, Piperacillin.

Answer 3

Extended-spectrum penicillins

Question 4

Broader spectrum than penicillins and cephalosporins, generally beta lactamase resistant

Answer 4

carbapenems

Question 5

Clavulanic acid and salbactam

Answer 5

class A beta lactamase inhibitors

Question 6

Cefalexin, cefuroxime, cefotaxime, cefadroxil

Answer 6

cephalosporins, an alternative to penicillins

Question 7

Vancomycin

Answer 7

Glycoptide, binds to peptide chain

minimal resistance

Question 8

Bacitracin

Answer 8

cyclic peptide
skin and eye infections
bactericidal
cell wall inhibitor

Question 9

sulphonamides and trimethoprim

Answer 9

folate antagonists

Question 10

Tetracycline

Answer 10

30s inhibitor

Question 11

chloramphenicol, erythromycin, clindamycin, streptogramins

Answer 11

50s inhibitor

Question 12

Erythromycin and

clarithromycin

Answer 12

Macrolide
alternative to penicillin

erythromycin- long QT syndrome

Question 13

aminoglycosides

Answer 13

renal toxicity, ototoxicity, neuromuscular block
IV administration

protein synthesis inhibitor

Question 14

tetracyclines

Answer 14

targets 30s
resistant gram negative infection
gut problems, hepatic and renal dysfunction

Question 15

chloramphenicol

Answer 15

broad spectrum
risk of aplastic anaemia

50s