Tuberculosis Flashcards

1
Q

What is the primary infectious agent of Tuberculosis?

A

Mycobacterium Tuberculosis

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2
Q

The initial infection usually occurs

A

2 to 10 weeks after exposure

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3
Q

Fibrous tissue mass formed during infection.

A

Ghon Tubercle

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4
Q

For prevention recommendations, how many air exchanges per hour?

A

six (6) air exchanges per hour

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5
Q

For AFB isolation precautions, what room should the patient with TB should be in?

A

A room with negative pressure

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6
Q

If the patient is infected with TB, the chest x-ray usually reveals

A

lesions in the upper lobes.

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7
Q

is a standardized, intracutaeneous injection procedure for TB testing.

A

Mantoux Method

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8
Q

PPD

A

Purified Protein Derivative

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9
Q

Approximately how many inches below the elbow is PPD injected?

A

Approximately 4 inches below the elbow

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10
Q

The mantoux test result is read how many hours after the inejction?

A

48 to 72 hour after injection.

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11
Q

what is the term used for a raised hard area or swelling?

A

Induration

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12
Q

An induration of 0 to 4 mm is considered what?

A

considered as not signifcant.

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13
Q

An induration reaction of 5 mm or greater is

A

considered significant in people who are considered to be at risk of TB.

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14
Q

An induration of 10 mm or greater is what?

A

usually considered significant in people who have normal or mildly impaired immunity.

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15
Q

What do you call when a patient is immunosuppressed and cannot develop an immune response to produce a positive skin test?

A

Anergy

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16
Q

IGRA

A

Interferon Gamma Release Assay

17
Q

QFT-Plus Test

A

QuantiFERON-TB Gold Plus Test

18
Q

Resistance to two agents, Isoniazid and Rifampin

A

Multidrug Resistance (MDR TB)

19
Q

Resistance to isoniazid and Rifampin, in addition to any fluroquinolone, and at least one of three injectable second-line agents.

A

Extensively Drug Resistant (XDR TB)

20
Q

In current TB therapy, what are the four first-line medications used?

A

*Isoniazid
*Rifampin
*Pyrazinamide
*Ethambutol

21
Q

Treatment phases of pulmonary TB:

A

Initial Treatment and Continuation phase

22
Q

The initial treatment phase of TB consists of

A

Isoniazid, Rifampin, Pyrazinamide, and Ethambutol plus Vitamin B6 50 mg.

23
Q

The initial intensive-treatment is give daily for

A

8 weeks.

24
Q

The continuation regimen lasts for

A

4 or 7 months.

25
Q

Some people develop reactivation TB, this is also called as

A

Adult-type Progressive TB

26
Q

Spread or dissemination of TB infection to nonpulmonary sites of the body is known as

A

Miliary TB