Laryngeal Cancer

Question 1

the reason you’re able to make sounds, so it’s often called your voice box.

Answer 1

Larynx

Question 2

This flap closes during swallowing, forcing food down the esophagus and into the stomach.

Answer 2

Supraglottis

Question 3

It is in the center of your larynx (voice box). It
helps you breathe, speak and make sounds in
general.

Answer 3

Glottis

Question 4

It is the regulation of the temperature
of the breath.

Answer 4

Subglottis

Question 5

The flap that covers the trachea during swallowing so that
food does not enter the lungs.

Answer 5

Epiglottis

Question 6

It is a long, U-shaped tube that connects your larynx (voice box) to your lungs.

Answer 6

Trachea

Question 7

Malignant tumor of the larynx arise from the surface of the epithelium, classified as

Answer 7

squamous cell carcinoma.

Question 8

It is performed under local anesthesia or general anesthesia to evaluate all areas of the larynx.

Answer 8

Laryngoscopy

Question 9

A test to look inside your body.

Answer 9

Endoscopy

Question 10

It is an initial screening procedure to obtain samples of any larged lymph nodes in the neck.

Answer 10

Fine Needle Aspiration Biopsy

Question 11

It is used to assess regional adenopathy and soft tissues and to stage and determine the extent of a tumor.

Answer 11

CT Scan or MRI

Question 12

If the patient initially presents a chief complaint of difficulty swallowing, it is used to outline any structural anomalies of the neck that could pinpoint a tumor.

Answer 12

Barium Swallow

Question 13

It is used to detect recurrence of the
laryngeal tumor after treatment.

Answer 13

Position Emission Tomography (PET) Scan

Question 14

A platinum-based chemotherapy drug that causes DNA crosslinking, interfering with DNA replication and transcription. This induces apoptosis (cell death) in cancer cells.

Answer 14

Cisplatin

Question 15

It forms DNA crosslinks but has a different toxicity profile, causing less nephrotoxicity and ototoxicity.

Answer 15

Carboplatin

Question 16

An alternative to cisplatin for patients who cannot tolerate its side effects.

Answer 16

Carboplatin

Question 17

A pyrimidine analog that inhibits thymidylate synthase, disrupting DNA and RNA synthesis in rapidly dividing cells.

Answer 17

5-fluorouracil (5-FU)

Question 18

A taxane that stabilizes microtubules, preventing their depolymerization during cell division, leading to mitotic arrest and cell death.

Answer 18

Docetaxel (Taxotere)

Question 19

Similar to docetaxel, it stabilizes microtubules and inhibits cell division.

Answer 19

Paclitaxel (Taxol)

Question 20

An antifolate drug that inhibits dihydrofolate reductase, leading to reduced nucleotide synthesis and impaired DNA replication.

Answer 20

Methotrexate

Question 21

Surgeon removes part or all of the
vocal cords. An excision of the vocal cord.

Answer 21

Cordectomy

Question 22

It is to remove part of the larynx, or voice box, to treat early or recurrent laryngeal cancer. Used of often in the early stages of cancer in the glottic area when only one vocal cord is involved.

Answer 22

Partial Laryngectomy

Question 23

It removes the entire larynx, or voice box and some or all of the larynx.

Answer 23

Total Laryngectomy

Question 24

It uses the cutting power of laser beam to make bloodless cuts in tissue or to remove a surface lesion such as tumor.

Answer 24

Laser Surgery

Question 25

Removal of the mucosa of the edge of the vocal cord, using an operate microscope.

Answer 25

Vocal Cord Stripping

Question 26

is a surgical procedure performed to enable voice restoration in patients who have undergone a total laryngectomy (removal of the larynx).

Answer 26

Tracheoesophageal Puncture (TEP)

Question 27

This technique creates a direct connection between the trachea (windpipe) and the esophagus (food pipe) through a small opening or puncture. A voice prosthesis is then placed in this opening, allowing the patient to produce speech.

Answer 27

Tracheoesophageal Puncture (TEP)