Laryngeal Cancer Flashcards
the reason you’re able to make sounds, so it’s often called your voice box.
Larynx
This flap closes during swallowing, forcing food down the esophagus and into the stomach.
Supraglottis
It is in the center of your larynx (voice box). It
helps you breathe, speak and make sounds in
general.
Glottis
It is the regulation of the temperature
of the breath.
Subglottis
The flap that covers the trachea during swallowing so that
food does not enter the lungs.
Epiglottis
It is a long, U-shaped tube that connects your larynx (voice box) to your lungs.
Trachea
Malignant tumor of the larynx arise from the surface of the epithelium, classified as
squamous cell carcinoma.
It is performed under local anesthesia or general anesthesia to evaluate all areas of the larynx.
Laryngoscopy
A test to look inside your body.
Endoscopy
It is an initial screening procedure to obtain samples of any larged lymph nodes in the neck.
Fine Needle Aspiration Biopsy
It is used to assess regional adenopathy and soft tissues and to stage and determine the extent of a tumor.
CT Scan or MRI
If the patient initially presents a chief complaint of difficulty swallowing, it is used to outline any structural anomalies of the neck that could pinpoint a tumor.
Barium Swallow
It is used to detect recurrence of the
laryngeal tumor after treatment.
Position Emission Tomography (PET) Scan
A platinum-based chemotherapy drug that causes DNA crosslinking, interfering with DNA replication and transcription. This induces apoptosis (cell death) in cancer cells.
Cisplatin
It forms DNA crosslinks but has a different toxicity profile, causing less nephrotoxicity and ototoxicity.
Carboplatin
An alternative to cisplatin for patients who cannot tolerate its side effects.
Carboplatin
A pyrimidine analog that inhibits thymidylate synthase, disrupting DNA and RNA synthesis in rapidly dividing cells.
5-fluorouracil (5-FU)
A taxane that stabilizes microtubules, preventing their depolymerization during cell division, leading to mitotic arrest and cell death.
Docetaxel (Taxotere)
Similar to docetaxel, it stabilizes microtubules and inhibits cell division.
Paclitaxel (Taxol)
An antifolate drug that inhibits dihydrofolate reductase, leading to reduced nucleotide synthesis and impaired DNA replication.
Methotrexate
Surgeon removes part or all of the
vocal cords. An excision of the vocal cord.
Cordectomy
It is to remove part of the larynx, or voice box, to treat early or recurrent laryngeal cancer. Used of often in the early stages of cancer in the glottic area when only one vocal cord is involved.
Partial Laryngectomy
It removes the entire larynx, or voice box and some or all of the larynx.
Total Laryngectomy
It uses the cutting power of laser beam to make bloodless cuts in tissue or to remove a surface lesion such as tumor.
Laser Surgery
Removal of the mucosa of the edge of the vocal cord, using an operate microscope.
Vocal Cord Stripping
is a surgical procedure performed to enable voice restoration in patients who have undergone a total laryngectomy (removal of the larynx).
Tracheoesophageal Puncture (TEP)
This technique creates a direct connection between the trachea (windpipe) and the esophagus (food pipe) through a small opening or puncture. A voice prosthesis is then placed in this opening, allowing the patient to produce speech.
Tracheoesophageal Puncture (TEP)
