MYASTHENIA GRAVIS Flashcards
Myasthenia Gravis is an autoimmune disorder affecting the
myoneural junction
Two clinical types of Myasthenia Gravis:
*Ocular
*Generalized
drooping of the eyelids
Ptosis
voice impairment
Dysphonia
difficulty swallowing
dysphagia
A common test used to diagnose myasthenia gravis is
Acetylcholinesterase Inhibitor Test
Acetylcholinesterase test inhibitor is performed by
Administering Edrophonium Chloride IV
medication that control the side effects of edrophonium
Atropine
the ice test is indicated in patients who have
cardiac conditions or asthma
detects a delay or failure of neuromuscular transmission and is about 99% sensitive in confirming the diagnosis of Myasthenia Gravis
A single-fiber electromyography (EMG)
site of acetylcholine receptor antibody production.
Thymus Gland
is the first line therapy for Myasthenia Gravis.
Pyridostigmine bromide
it inhibits the breakdown of acetylcholine
Pyridostigmine bromide
inhibits T lymphocytes and B-cell proliferation and reduces acetylcholine receptor antibody levels.
Azathioprine
surgical removal of the thymus gland
Thymectomy
can produce antigen-specific immunosuppresion and result in clinical improvement.
Thymectomy
is an exacerbation of the disease process characterized by severe generalized muscle weakness and respiratory
Myasthenic Crisis