Peptic Ulcer Disease

Question 1

Peak onset of PUD

Answer 1

between 30 and 60 years of age

Question 2

a rare condition in which benign or malignant tumors form in the pancreas and duodenum that secrete excessive amounts of the hormone gastrin.

Answer 2

Zollinger-Ellison Syndrome

Question 3

Exact cause of Zollinger-Ellison Syndrome is unknown but are linked to an inherited genetic condition called

Answer 3

Multiple Endocrine Neoplasia Type 1 (MEN-1)

Question 4

Peptic ulcers occur mainly in the

Answer 4

gastroduodenal mucosa

Question 5

More than 80% of gastrinomas are found in the

Answer 5

“gastric triangle”

Question 6

acute mucosal ulceration of the duodenal or gastric area that occurs after physiologically stressful events

Answer 6

Stress Ulcer

Question 7

ulcer that is frequently observed after extensive burn injuries and often involves the antrum of the stomach or the duodenum

Answer 7

Curling Ulcer

Question 8

is common in patients with a traumatic head injury, stroke, brain tumor, or following intracranial surgery.

Answer 8

Cushing Ulcer

Question 9

silent peptic ulcers most commonly occur in

Answer 9

older adults and those taking aspirin and other NSAIDs

Question 10

Patient with an ulcer complains of

Answer 10

*dull, gnawing pain
*burning sensation in the mid epigastrium or the back

Question 11

The pain associated with gastric ulcer occurs

Answer 11

immediately after eating

Question 12

Pain associated with duodenal ulcers occurs

Answer 12

commonly 2 to 3 hours after meals.

Question 13

is the preferred diagnostic procedure because it allows direct visualization of inflammatory changes, ulcer, and lesion

Answer 13

Upper Endoscopy

Question 14

Recommended days for combination of drug therapy for ulcer

Answer 14

10 to 14 days

Question 15

Triple combination therapy for Ulcer

Answer 15

*Two antibiotics (Metronidazole and clarithromycin)
*Proton Pump Inhibitor (Omeprazole)

Question 16

Quadruple Therapy for Ulcer

Answer 16

*Two Antibiotics (Metronidazole and Tetracycline)
*Proton Pump Inhibitor
*Bismuth Salts

Question 17

medications used to treat ulcers not associated with H. Pylori Infection

Answer 17

*H2 Blockers
*Proton Pump Inhibitors

Question 18

Maintenance dosages of h2 blockers are usually recommended for

Answer 18

1 year

Question 19

For patients with ZES, hypersecretion of gastrin stimulates the release of gasctric acid, a medication like ____ that suppresess gastrin levels may also be prescribed.

Answer 19

Octreotide