Treponema

Question 0

Two ways of transmitting T.pallidum

Answer 0

Bet sexual partners

Fr mother to fetus

Question 1

Etiologic agent of syphilis

Answer 1

Treponema pallidum

Question 2

T.pallidum is
A.aerobic
B.microaerophilic
C.aerotolerant
D.facultative anaerobic

Answer 2

B

Question 3

Which can be done to T.pallidum?
A.in vitro culture
B.light microscopy
C.dark field microscopy
D.all 3

Answer 3

C

Also: fluorescent antibody technique

Question 4

True / False

Invasion of CNS can occur during any stage of syphilis

Answer 4

True

Question 5

In primary syphilis, a lesion called ___ develops

Answer 5

Chancre

Question 6

False abt chancre
A.painful and hard
B.no ulcer and inflammatory zone
C.incubation is 3 weeks
D.bilateral lymphadenopathy

Answer 6

A.

Painless ang chancre

Question 7

In secondary syphilis, __ lesions are most common

Answer 7

Mucocutaneous

Question 8

Characteristic penile and vaginal lesions that are similar to genital warts made by HPV

Identify

Answer 8

Condylomata lata

Question 9

Serologic tests for syphilis may not be positive during early primary syphilis. T or F?

Answer 9

T

Question 10

Serologic tests for syphilis are usually at their lowest titer during secondary syphilis. T or F?

Answer 10

F

Highest dapat

Question 11

In latent syphilis, the only evidence is the __

Answer 11

Positive serologic test for syphilis

Question 12

What is the common clinical manifestation between early neurosyphilis and late neurosyphilis?

Answer 12

Ocular involvement

Question 13

Identify: central necrosis, deep ulcer with a gummy base

Answer 13

gumma

Question 14

T or F: Congenital syphilis may occur only during tertiary syhilis.

Answer 14

False

Any stage dapat

Question 15

Which is not a direct manifestation of congenital syphilis?
A. mucous patches
B. Hutchinson's teeth
C. cerebral palsy
D. perforation of palate

Answer 15

C

Question 16

Which is false?
A. Treponemal tests are qualitative.
B. Nontreponemal tests are both qualitative and quantitative.
C. The use of one quantitative test is enough for diagnosis
D. Both types of serological test may be reactive for life

Answer 16

C

one is not enough

Question 17

Which method measures antibody directed T.pallidum antigens?
A. treponemal
B. nontreponemal
C. both A and B
D. neither A nor B

Answer 17

A

Question 18

Which method measures antibodies directed against a cardiolipin-lecithin cholesterol antigen?
A. treponemal
B. nontreponemal
C. both A and B
D. neither A nor B

Answer 18

B

Question 19

T or F

In nontreponemal tests, only false positive tests may occur.

Answer 19

F

prozone effect may also cause false negative tests.

Question 20

In diagnosing latent syphilis, which is not a criteria?
A. 3-fold increase compared to serologic titer obtained within the year preceding the evaluation
B. seroconversion
C. contact to infectious syphilis case
D. none of the above

Answer 20

A

4-fold dapat

Question 21

T or F: Neurosyphilis may occur at any stage of syphilis

Answer 21

T

Question 22

What is the standard serological test for CSF?

Answer 22

VDRL-CSF

Question 23

False about Neurosyphilis diagnosis
A. CSF leukocyte count is usually high in people with neurosyphilis
B. When VRDL-CSF is reactive in the absence of contamination of the CSF with blood, the patient has neurosyphilis.
C. If VRDL-CSF is positive but there are no clinical manifestations, the patient is likely to not have neurosyphilis.
D. All are true.

Answer 23

C

positive VRDL-CSF –> neurosyphilis, with or without clinical manifestations.

Question 24

___ is the drug of choice for primary, secondary, early latent and late latent syphilis

Answer 24

Benzathine Penicillin G

Question 25

___ is the drug of choce for neurosyphilis

Answer 25

Aqueous crystalline penicillin G

Question 26

What is Jarrisch-Herxheimer reaction?

Answer 26

self-limited reaction to anti-treponemal therapy

Question 27

T or F: Jarrisch-Herxheimer reaction is caused by an allergic reaction to penicillin

Answer 27

F

Question 28

Causative agent of YAWS

Answer 28

Treponema pallidum subspecies Pertenue

Question 29

In early yaws, a primary papule/group of papules appear at the site of inoculation after 3 weeks of incubation. This usually becomes large and crusted. this is called:

Answer 29

Mother Yaw/Maman pian

Question 30

secondary yaws: smaller, form around primary lesion, also called: ___

Answer 30

ringworm yaws

Question 31

What are crab yaws?

Answer 31

hyperkeratotic plaques that form around palms and soles

Question 32

___ yaws: ulcer with clean edges that tend to fuse to form configurate and serpinginous patterns similar to tertiary syphilis

Answer 32

late

Question 33

another name for endemic syphilis

Answer 33

Bejel

Question 34

causative agent of bejel

Answer 34

T.pallidum subspecies Endemicum

Question 35

``` true about secondary lesions @ bejel A. painful buboes B. painless ulcers C. do not grow at all D. hyperkeratotic plaque ```

Answer 35

B

Question 36

``` true about secondary lesions @ bejel A. gummatous ulcerations B. painless ulcers C. do not grow at all D. hyperkeratotic plaque ```

Answer 36

A

Question 37

causative agent of pinta

Answer 37

T. carateum

Question 38

``` false about primary stage of pinta A. 7-60 days after inoculation B. with erosion but not ulcer C. tiny red papule, becoming more infiltrated D. all of the above ```

Answer 38

B no erosion and no ulcer

Question 39

false about secondary stage of pinta A. nontreponemal tests are not reactive in all cases B. small scalingpapules that enlarge and coalesce C. 5 months to 1 yr D. all of the above

Answer 39

A they are reactive to 60% of the cases

Question 40

the late dyschronic stage of pinta : hyperpigmented macules, or depigmented macules resembling ___

Answer 40

vitiligo

Question 41

Yaws, Bejel and Pinta are all what kind of treponematoses?

Answer 41

nonvenereal treponematoses