Rubella Flashcards
genus of Rubella
Rubivirus
false about Rubella A.one antigenic type B.naked virus C.single strand positive sense RNA D.icosahedral nucleocapsid
B
enveloped dapat
Rubella glycoprotein components: enumerate
E1
E2
host cell derived lipid
icosahedral nucleocapsid components:enumerate
C protein
ssRNA
enumerate 3 major virion polypeptides of rubella virus
C protein
E1
E2
antigen in rubella that agglutinates chick, pigeon, goose and type O human RBC
Hemagglutinating Ag
Where does rubella virus replicate?
cytoplasm
Which is false?
A. Rubella is zoonotic.
B. Rubella may be transmitted via inhalational or transplacental.
C. Peak of rubella infection is during late winter and spring.
D. Rubella is communicable 7 days before and after the onset.
A
humans: only host
In postnatal rubella, in what organ does the virus replicate?
nasopharynx
T or F: Placenta and fetus may be infected in viremia of postnatal rubella.
T
Sequence the clinical features of rubella
A. Maculopapular rash
B. Prodromal
C. Lymphadenopathy
B C A
Identify enanthem of rubella + locatiion
Forschheimer spots @ soft palate
most common complication of postnatal rubella
arthralgia/arthritis
False about Rubella reinfection
A. occurs in a person with natural rubella or vaccine
B. IgG antibody response is higher with equiocal IgM titer
C. uncommon to cause unequivocal fetal damage
D. with visible symptoms
D
most common manif of Congenital Rubella Syndrome
intrauterine growth retardation
most common clinical feature of Congenital Rubella Syndrome
deafness
[Congenital Rubella]
slow cell div, disoriented cell diff, small BV damages: in what trim does this occur?
1st
Specific Ig @ less than __ months indicates (+) Congenital Rubella
12
if 9-12 months, check if there’s maternal Ab inteference
method of choice for Congenital Rubella diagnosis indluse all except:
A.virus isolation
B.ELISA
C.immunofluorescent absorbent assay
A
passive prophylaxis of rubella
human immunoglobulin
live virus for rubella artificial active immunity – what is the composition?
RA 27/3 Strain
ELISA may be used to measure Ig\_\_ A. G B. A C. E D. M
D
