Subcutaneous Mycoses Flashcards
How are lesions/pathologic effects of subcutaneous mycoses able to spread throughout the body?
Lymphatic channels
Resulting lesions of subcutaneous mycoses are all ___ lesions.
Granulomatous
Causative agent of Rose gardener’s disease
Sporothrix schenkii
How do etiologic agents of subcutaneous mycoses enter the body?
Traumatic inoculation
false about Sporothrix schenkii A. branching and septate hyphhae B. hyphae arranged in flowerlike clusters C. dimorphic fungus D. with neuraminidase
B
conidia dapat
Which is not a means of entry for Sporothrix schenkii? A.animal or insect bites B.splinters C.contaminated wound dressings D.sexual contact
D
Rose gardener’s disease produces lesions usually found at (A) for adults and (B) for kids
(A) lower extremities
(B) face
this type of sporotrichosis cases is found in ~75% of cases; it forms sporotrichiotic chancre
lymphocutaneous sporotrichosis
in chronic sporotrichosis, what happens to the lymph channels?
become hard and cord-like
most reliable way to diagnose S.schenkii
culture (thermal conversion)
T or F. Serology is still very helpful in sporotrichosis diagnosis.
F
Exophiala jeanselmei
Pseudolescheria boydii
Madurella mycetomatis
Madurella grisea
these cause what specific mycoses?
mycetoma
what is mycetoma?
it is interconnecting and it drains sinuses
best way to diagnose mycetoma
culture
false about Madurella morphology
A. white granules
B. air space
C. club-shaped hyphae
A
black dapat
Phialophora verrucosa
Fonsecaea pedrosoi/compacta
Cladosporium carrionii
Rhiniocladiella aquaspersa
All these may cause what specific mycoses?
chromoblastomycosis
all EAs of chromoblastomycosis have what color of hyphae?
dematiaceous/dark
Pathogenesis of Chromoblastomycosis
- tissue prolif
- wartlike lesion
- ______________
cauliflower nodules
sclerotic bodies may be found in what specific mycoses?
chromoblastomycosis
Rhiniocladiella aquaspersa & Fonsecaea pedrosoi : type of conidation
acrotheca
Which has smaller conidia?
Fonsecaea pedrosoi/compacta
Fonsecaea compacta
Causative agent of Entomophthoromycosis
Conidiobolus coronatus
False about Conidiobolus coronatus
A.slow growing colony
B.zygomycete
C.non-septate hyphae
A
fast dapat
Entomophthoromycosis - where does swelling begin?
nasal area
in media w/o ____, spherical conidia with numerous branching hyphae are seen. for Conidiobolus coronatus
cyclohexamide
common about epidemiology of Lobomycosis,Entomophthoromycosis and Sporotrichosis
more prevalent in males
sequelae of germination of sporangiospores in nasal passages; may be caused by Rhizopus
Rhinocerebral mucormycosis
Rhinocerebral mucormycosis may lead to what ocular complication?
orbital cellulitis
inhalation of sporangiospores may lead to. __
thoracic mucormycosis
morphology of mucormycosis EA @ H&E stain
infrequently septate, thin-walled hyphae, with irregular branching
causative agent of rhinosporidiosis. Can it be cultured?
Rhinosporidium seeberi
no
What is rhinosporidiosis?
chronic granulomatous disease of mucocutaneous tissue.nose: main target
Lacazia loboi causes lobomycosis and is cross antigenic with ___
Paracoccidioides brasilienses
lesions of lobomycosis resemble what bacterial infection?
leprosy
When Lacazia loboi is mounted on Periodic Acid Schiff stain, what can be seen?
yeast cells inside macrophages
Which geographic subpopulation has the most number of lobomycosis?
Calabi Indians
What do Alternaria and Curvularia cause? (specific type of mycoses)
cause Phaeohyphomycosis
False about EAs of Phaeohyphomycosis
A.dematiaceous with aseptate hyphae
B.black fungi in fruits
C.mycelia in morphology
A
with septa
Identify causative agent of Phaeohyphomycosis
- macro: yeastlike, with short aerial hyphae
- micro: rocket-shaped mature conidiogenous cells with tapering zones
Exophiala jeanselmei
T or F
Exophiala spinifera’s optimal temperature for growth is 40 deg C
F
It does not grow at 40 deg C
Special medium where Cladophialophora bantiana grows
Potato Dextrose Agar
causative agent of cerebral phaeohyphomycosis
Cladophialophora bantiana
Enumerate causative agents of SubCT Phycomycosis
Basidiobolus haptosporus
Basidioolus ranarum
False about microculture for Basidiobolus haptosporus //
Basidioolus ranarum
A. invaded vasculature
B. branching hyphae with infrequent septa
C. giant cells with multiple granulomata
D. inhibited by cyclohexamide
A
vasculature not invaded
