Arboviruses Flashcards
Which is not a Bunyavirus? A.Rift Valley fever B.Crimean Congo hemorrhagic fever C.Sandfly fever D.Dengue hemorrhagic fever
D
Humans may be \_\_ hosts of Arboviruses. A.intermediate B.definitive C.accidental D.A & B E.B & C
E
Which is not a member of Flaviviridae? A.Japanese encephalitis B.Yellow fever C.Chikungunya D.Dengue hemorrhagic fever
C
Chikungunya is a member of Togaviridae
Which is not common in our country? A.Japanese encephalitis B.Yellow fever C.Chikungunya D.Dengue hemorrhagic fever
b
A)Family Flaviviridae
B)Enveloped
C)(+)ssDNA virus
D)fifth genotype still under observation
False abt dengue virus
C
(+)ssRNA dapat
False about Aedes mosquito
A)Infected male mosquito transmits dengue
B)Found in tropical and subtropical areas
C)Breed in clean, stagnant water
D)none of the 3
A
Female dapat
False about Aeses
A.Primarily a nocturnal feeder
B.Live around human habitation, generally “indoor”
C.Lay eggs and produces larvae preferentially in artificial containers
A
Daytime dapat
Aedes species that is Usually found outdoors (in stagnant waters collected on banana trees)
Aedes albopictus
Which is false?
A)Attachment to specific receptors on many different cell types from many different species
B)When coated with antibodies, Ig can attach to Fc receptors on surface of macrophages and monocytes
C)Both are false
D)Both are true
B
Antigens, not antibodies
\_\_ binds to the virus (second infection) and forms the “infectious complex” A. IgE B. IgG C. IgM D. IgA
B
“infectious complex” binds to \_\_receptor on surface of macrophages & monocytes A)Fa B)Fab C)Fbc D)Fc
D
Virus is taken up by \_\_ A.exocytosis B.pinocytosis C.endocytosis D.transcytosis
C
Sequence
A)Recognition of viral antigens on the surface of infected
B)T-cell proliferation
C)Induction of memory T-cell
D)T-cell lyses the virus
C B A D
Mesenchymal Cells →Plasma leakage→ SHOCK→ Hemostatic system→ Hemorrhage
What is wrong with the pathogenesis of dengue?
Endothelial, not mesenchymal
Classical dengue vs dengue hemorrhagic fever: main difference
Classic dengue- severe myalgia
Dengue hemorrhagic fever- bleeding
Hematemesis is \_\_ A.vomiting of blood B.passage of black and tarry stools C.passage of fresh blood through anus with or in stools D.none of the above
A
Melena is A.vomiting of blood B.passage of black and tarry stools C.passage of fresh blood through anus with or in stools D.none of the above
B
Hematochezia is A.vomiting of blood B.passage of black and tarry stools C.passage of fresh blood through anus with or in stools D.none of the above
C
All are definitive symptoms of DHF except A.melena B.hematemesis C.hematochezia D.myalgia
D
Enumerate theories on DHF Pathogenesis
Antibody enhancement theory
Viral virulence theory
Antibody enhancement theory is AKA __
Halstead’s Theory
Viral virulence theory is AKA __
Rosen’s Theory
False about Halstead’s Theoy
- secondary dengue is not a risk factor
- heterotypic antibodies from a previous infection promote increased viral replication within mononuclear leukocytes
- immunologic processes occur
- dengue virus-infected cells are eliminated
1
Treatment for dengue
Fluid replacement
