Opportunistic Mycoses Flashcards
only opportunistic fungal species that exhibits thermal dimorphism
Candida albicans
Which is false?
A. Diagnosis of opportunistic mycoses does not require high index of suspicion.
B. The lower your host’s resistance is, the higher the chances of disease.
C. Anti-neoplastics, TB and AIDS may increase one’s chance of getting opportunistic mycoses.
A
Candida grows best at __ pH
A.acidic
B.Neutral
C.Alkaline
C
Which is not caused by Candida? A.oral thrush B.angular cheilitis C.balanitis D.fungus balls
D
D c/o aspergillosis
balanitis:candidiasis @ penis
identify: typical skin lesions of Candida, especially @ the feet
satellite lesions
The ff are adjectives used to describe Candida lesions except A.whitish B.erythematous C.dematiacous D.none of the above
C
What makes C.glabrata unique? A.no thermal dimorphism B.no pseudohyphae C.no yeast cells D.A and B E.B and C
D
easiest and fastest way of differentiating Candida species
Germ tube formation
in CHROMagar media, C.albicans produces culture that is color A.green B.pink C.yellow D.white
a
in CHROMagar media, C.glabrata produces culture that is color A.green B.pink C.yellow D.white
B
Which Candida species produces germ tube
Candida albicans
Basidiomycetous yeasts with large polysaccharide
capsules, found in dry pigeon feces or trees @ tropical regions
A.Aspergillus
B.Candida
C.Cryptococcus
D.Rhizopus
C
A.whitish mucoid colonies
B.with capsule
C.possess urease
D.with pseudohyphae
false about Cryptococcus
D
phenol oxidase, which catalyzes
the formation of melanin from appropriate phenolic
substrates
laccase
laccase is found in which Cryptococcus species?
C. neoformans
C. gattii
main components of Cryptococcus’ capsular polysaccharide
polymannose,xylose and glucuronic acid.
Cryptococcus can produce __, which protects it from oxidative killing
melanin
False about culture of Cryptococcus
A. Slimy or mucoid colonies
B. Growth is promoted by cycloheximide
C. Can be identified by the detection of urease
D. Brown pigment due to phenol oxidase (or laccase)
B
inhibited dapat
main complications of Cryptococcus involves A.stomach B.heart C.lungs D.all of the above
C
The ___ for cryptococcal
antigen is positive in 90% of patients with cryptococcal
meningitis.
The latex slide agglutination test
false about Aspergillus A. Branching, aseptate mycelium B. Characteristic conidial head C. Mold form D. Invades the lungs and other tissues
A
septate dapat
most common Aspergillus species that causes disease
Aspergillus fumigatus
Which does not have a clavate head?
A. Aspergillus fumigatus
B. Aspergillus niger
C. Aspergillus flavus
B (Globate head kasi)
Which does not have smooth conidiophore?
A. Aspergillus fumigatus
B. Aspergillus niger
C. Aspergillus flavus
C (pitted conidiophore kasi)
true or false: Aspergillus fumigatus is inhibited by cyclohexamide
True
false about Aspergillus fumigatus
A. produces aerial hyphae
B. long conidiophores with terminal vesicles
C. phialides (at vesicles)produce basipetal chains of conidia
D. septated, dichotomous, 90° angle branching hyphae
D
45 degrees dapat
allergic bronchopulmonary aspergillosis ensues when the fungus ___
Colonizes the bronchial tree without invading
the lung parenchyma
Which does not happen in allergic bronchopulmonary aspergillosis?
A.asthma
B.recurrent chest infiltrates
C.eosinophilia
D.both type I & II hypersensitivity to Aspergillus antigen
D
I and III dapat
Aspergillus fumigatus creates ___ when its inhaled conidia enter an existing cavity, germinate, and produce abundant hyphae in the abnormal extrapulmonary spaces.
fungus balls
A.Hyphae invade the lumens and walls of the blood
vessels, causing thrombosis, infarction, and necrosis
B. From the lungs, it may spread to the gastrointestinal
tract, kidney, liver, brain, or other organs, producing
abscesses and necrotic lesions
identify the clinical manif caused by Aspergillus fumigatus
invasive aspergillosis
Serologic test for circulating cell wall ___ is
diagnostic for aspergillosis
galactomannan
in histologic sections, the hyphae of Aspergillus fumigatus are uniform in width and branch at ___ angle
dichotomously
acute
Where can surgery be used as treatement?
A.Aspergilloma
B.Allegic Bronchiopulmonary Aspergillosis
C.Extrinsic allergic alveolitis
A
For Amphotericin B-resistant strains of A. terreus and
other species including A. flavus and A. lentulus,
__ is used.
Posaconazole
Corticosteroids or Disodium Chromoglycate are used in treatment of?
A.Aspergilloma
B.Allegic Bronchiopulmonary Aspergillosis
C.Extrinsic allergic alveolitis
B
A)Rhizopus
B)Absidia
C)Cunninghamella
D)Exophiala
Which does not cause mucormycosis?
D
identify the clinical manifestation of mucormycosis
A. Results from germination of the sporangiospores in the
nasal passages and invasion of the hyphae into the
blood vessels
B. Patients develop facial edema, bloody nasal exudate, and orbial cellulitis
rhinocerebral mucormycosis
morphology of zygomycosis etiologic agents A. septate with right angle branching B. aseptate with right angle branching C. aseptate with acute angle branching D. septate with acute angle branching
B
drug for mucormycosis
amphotericin B,
opportunistic fungus that cause pneumonia in AIDS patients
Pneumocystis jiroveci
enumerate the two forms of Pneumocystis jiroveci
Thin-walled trophozoites
Thick-walled cysts
There probably is P.jiroveci if __ are seen in chest radiography
bilateral infiltrates.
Which is not an appropriate stain for micro exam of P.jiroveci? A.Giemsa B.Gram C.methenamine silver D.calcofluor white
B
T or F. Pneumocystis jiroveci can be cultured.
F
The only dimorphic penicillium
Penicillium marneffei
