Transplantations Flashcards
Is the process of?
taking cell, tissues or organs called CRAFT from the DONOR and placing them into RECIPIENT
Autologous graft?
graft from one individual to same individual
Syngenic graft?
transplant between 2 genetically identical individuals
Allogenic graft?
transplant between two genetically different individuals
Xenogenic graft?
transplant between two diff species
Molecules that are recognized as foreign on allograft are called
alloantigens
Alloantigens elicit what immune response?
Cell mediate and humoral immune
Recognition of transplanted cells as self or foreign is determined by
Polymorphic genes that inherit from both parents and are expressed codominantly.
Culturing of cells in done…
in vitro - allow to grow
Tissue culture
allows for cells to migrate from tissue and grow
All mammalian cells have limited or unlimited potential of cell division
limited
Immortalized cell lines have
unlimited potential to grow so we can gradually
passage them. Immortalization is achieved by chemical or physical carcinogens or
by viral infection – transformed cell lines
They grow in (conditions)…
medium containing energy source, minerals, amino acids, buffer, dye,
antibacterial + antifungal agents.