Hematopoiesis, blood cell types, blood characteristics

Question 1

What is it?

Answer 1

process of blood formation in bone marrow

Question 2

What are the two phases?

Answer 2

Prenatal

• Extra-embryonic – yolk sack
• Intra-embryonic – foetal liver, spleen, bone marrow

Postnatal phase – Bone marrow
Children – long bones
Adults – cranium, pelvis, vertebrae, sternum.

Question 3

It is pluripotent so…

Answer 3

potential to develop into any type of blood cell.

It first develops into hematopoietic progenitors, which are specific for
blood lineage

Question 4

Granulopoiesis

Answer 4

1 nuclear shrinkage and segmentation
2 condensation of the chromatin
3 increase in cytoplasmic matrix amount

Question 5

Erythropoiesis

Answer 5

1 reduction in size
2 nuclear shrinkage
3 chromatin condensation
4 increase in cytoplasmic matrix amount
5 decrease in RNA amount

Question 6

Hierarchy of Haematopoiesis

Answer 6

Stem cell, multipotent progenitor, committed progenitor, mature cells