Antibody structure and genetics Flashcards
1
Q
How do they look?
A
Large Y shaped protein (tertiary protein)
two identical heavy and light chains
constant region w. disulfide bridges in between.
antigen binding site (which is variable)
2
Q
Where are they produced?
A
produced and secreted by Plasma cells
3
Q
Origin of immunoglobins?
A
polymorphism
4
Q
2 types of immunoglobins
A
Heavy chain - chromsome 14 - including IGS, B cell receptor
Light chain - chr 2 and 22
T cell receptors from alpha chain 14 and beta 7
