Cell cycle and cell division Flashcards
In prokaryotes?
lack cell nucleus, therefore, cycle is fast + simple, 30 mins
- binary fission(asexual reproduction)- DNA replication (duplication of
chromosomes); continued cell growth (cell elongation); septum formation causing
division of daughter cells. (each daughter cell receives one copy of chromosome).
In eukaryotes?
INTERPHASE-
G1- cell content doubles + grows to be able to support 2 cells.
S phase- DNA replication; during this phase mutations can occur which
can lead to evolution, or disease
G2 – cell ensures if DNA replication is complete + further growth
MITOSIS:
1. Prophase –nuclear envelops disintegrates, DNA condenses + chromosomes
are visible, centrioles start to move to opposite poles.
2. Metaphase – chromosomes line up on equator, mitotic spindle forms from
centrioles to centromeres on chromosomes
3. Anaphase- spindle contracts + chromosomes split from centromeres (sister
chromosomes) + move towards opposite poles of cell
4. Telophase – nuclear envelop reforms
- Cytokinesis – formation of cell membrane around 2 new daughter cells.
What is p53 coded by?
tp53 tumor suppressor gene and inhibits CDK