Total Intravenous Anesthesia and Analgesia Flashcards

1
Q

what goals are you trying to acheive with GA (not matter which technique is used) `

A

unconsciousness

immobility

antinociception

muscle relaxation

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2
Q

T/F Intubation and administration of 100 % O2 is beneficial for every anaesthetized patient regardless of the anesthetic technique and agent of choice!

A

TRUE!

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3
Q

what are some disadvantages to TIVA

A

drugs may accumulate

more difficult to monitor and control anesthetic depth

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4
Q

elimination half-life changes with

A

duration of infusion

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5
Q

ideal agent for TIVA should be..

A

short acting

stable and short context sensitive half-life

no active metabolites

wide therapeutic window

smooth recovery

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6
Q

TIVA most commonlu consists of

A

CRI of an anesthetic and an analgesic

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7
Q

common anesthetics used for TIVA

A

propofol, alfaxalone, ketamine

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8
Q

common analgesics used for TIVA

A

opioids, lidocaine, ketamine, alpha 2 agonist

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9
Q

common adjuvants (to aid in muscle relaxation) with TIVA

A

benzodiazepines, guaifenesin

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10
Q

what is the most common TIVA

A

propfol - fentanyl

start CRI higher and reduce rate later on

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11
Q

Alfaxalone TIVA

A

doesnt seem to accumulate

may be combined with opioid analgesics

Tx disphoria during recovery with sedatives

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12
Q

T/F etomidate is not a option for TIVA

A

True

inhibits cortisol secretion

accumulation of propylene glycol

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13
Q

which drug can accumulate after large or repeated doses causing a delayed and rough recovery

A

ketamine

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14
Q

when is a ketamine based TIVA suitable

A

Field Procedures

triple drip - horses (GG, xylazine, ketamine)

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15
Q

Analgesics infusions can be used…

A

as part of TIVA/PIVA to reduce dose of anesthetic and provide antinoceception

can be used alone for analgesia - e.g. post OP or in ICU

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16
Q

Opioid CRIs

A

mostly small animals

fentanyl, morphine

17
Q

Lidocaine CRI

A

relief of abdominal pain in colic horses

adbominal and neuropathic pain in dogs

18
Q

can lidocaine CRIs be given to cats

A

no - contraindicated in cats

potential cardiotoxic effects

19
Q

T/F there is a narrow therapeutic window with Lidocaine

A

True

20
Q

ketamine CRI

A

can be used as analgesic infusion

commonly combined with opioids

21
Q

MLK infusion

A

morphine, lidocaine and ketamine

(skip lidocaine in cats)

22
Q

MLK for horses

A

lidocaine - ketamine infusion reduce MAC and suitable for colic

opioids dont reduce MAC but do not impair quality of recovery

23
Q

dexmedetomidine CRI for small animals

A

sedative, analgesic and antiepileptic

24
Q

dexmedetomidine CRI in horses

A

reduces MAC by 20-30%

can be substituted with other alpha 2 agonists

Not suitable for risk patients (colic) - adverse CV effects