Pregnancy and Cesarean Section Flashcards
cardiovascular changes in pregnant animals
CO increases 30-50%
- heart rate
- stroke volume: increased blood volume, decreased vascular resistance (afterload)
- blood pressure unchanged
T/F RBC increase > plasma volume increase
False
plasma volume increase > RBC increase → decrease PCV
T/F aortocaval compression decreases venous return
True
pregnant patients have a decreased _______ reserve
cardiac
what is the progesterone effect on the the respiratory center
decreased PaCO2 - hyperventilation
≈ 30 mmHg at time of parturition
what is the cause of decreased pulmonary resistance in pregnant animals
progesterone → relaxation of bronchial smooth mm.
pregnant animals have a(n) increased/decreased functional residual capicity (FRC)
decreased
increased abdominal volume
GI changes in pregnant animals
delayed gastric emptying
increased gastric acidity
decreased lower esophageal sphincter tone
increased risk of reguritation/aspiration
causes of delayed gastric emptying
pressure from uterus
decreased gastric motility
increased progensterone
renal changes with pregnancy
increased GRF (increased CO)
decreased BUN and CREA
pharmacolic changes in the dam
decreased MAC
increased sensitivity to local anesthetics
pharmocologic considerations for the fetus
most drugs easily cross placenta
fetal drug metabolism is slow - immature hepatic microsomal enzyme system
what is the ideal drug protocol
maximize O2 delivery to fetus - maintain CO and oxygenation, avoid uterine contraction/vasoconstriction
minimize drug effects on fetus
sedative use in small animal
not recommended
- acepromazine & benzodiazepines - fetal depression*
- alpha 2 agonist - decrease CO*
T/F alpha 2 agonists are used routinely in mares despite increased uterine pressure and decreased O2 delivery to the fetus
True
which alpha 2 agonist may cause less of an increase in uterine tone compared to xylazine
detomidine
which sedative is commonly used with ketamine in large animals
benzodiazepines
how should opioids be given
administer to mom after pups out
can reverse pups as pull out
how long does fetal elimination of opioids take
2-6 days