Topic 9: CKD & Dialysis Flashcards
CKD
involves progressive, irreversible loss of kidney function. Defined as wither presence of kidney damage or decreased GFR less than 60mL/min for longer than 3 months
Last stage of kidney disease is end-stage renal disease (ESRD), occurs when the GFR is
less than 15mL/min
leading causes of CKD
diabetes and HTN
Clinical Manifestations of CKD
· Retained urea, creatinine, phenols, hormones, electrolytes, water
· Uremia: a syndrome in which kidney function declines to a point that symptoms may develop in multiple body systems (occurs when GFR is 15mL/min or less)
· Difficulty with urine retention OLIGURIA
Increased BUN and Creatinine (waste product accumulation
· Kussmauls breathing (with severe acidosis)
· Dyspnea (fluid overload, pulmonary edema, etc.)
Increased BUN manifestations
N/V, lethargy, fatigue, impaired thought process, HA
CKD alters carbohydrate metabolism which means
client may present with Moderate hyperglycemia and hyperinsulinemia
most patients with CKD die from
CVD: increased LD and Low HDL
electrolyte imbalances associated with CKD
hyperkalemia
hypernatremia
hyperphospatemia
hyperkalemia can lead to
can lead to fatal dysrhythmias
Impaired sodium excretion for CKD can lead to
edema, HTN and HF
in CKD kidneys are unable to excrete acid which means
Metabolic acidosis
why is anemia a manifestation in CKD
due to decreased production of ERYTHROPOETIN
neurologic changes in CKD (Result of increased nitrogenous waste products)
lethargy, apathy, decreased ability to concentrate, fatigue, irritability, altered mental status
· CKD mineral and bone disorder
o Kidney is not turning vitamin D into its activated form, decreased vitamin D means decreased serum calcium levels
o This means hyperphosphatemia
o Increase risk for BONE FRACTURE
· Uremic frost
o Rare condition in which urea crystalizes on the skin
o Usually only seen when BUN levels are really high
what is usually the first sign of kidney damage
Persistent proteinuria (dipstick evaluation)
diagnostic assessment for CKD
· Renal ultrasound, renal san, CT scan
· Renal biopsy
· BUN, creatinine and creatinine clearance levels
· Serum electrolytes
· Lipid profile
· Urinalysis
· Protein-to-creatinine ratio in first morning voided specimen
· Hematocrit and hemoglobin levels
stage 1 CKD
GFR >90
stage 2 CKD
GFR 60-89