Topic 8: Breast Cancer Flashcards
lobules
milk-producing glands
ducts
milk passages that connect the lobules and the nipple
Breast cancers can in situ are within the…
duct
invasive breast cancers are evading…
through the wall of the duct
Metastatic breast cancer has spread to
other organs
Risk factors of breast cancer
· Women over the age of 50 (after 60 the incidence increases dramatically)
· Hormone therapy
· Oral contraceptive use
Mutations in the BRCA 1 and BRCA 2 genes
Clinical Manifestations of breast cancer
· Usually detected as a lump or thickening of the breast or mammography abnormality
· Nipple discharge (can be clear or bloody)
· Nipple retraction may occur
· Infiltration, induration, dimpling pulling in of the overlying skin
where are lumps usually found on the breast
o Often on the upper outer quadrant of the breast
Side effects of Lumpectomy
· Breast soreness
· Breast edema
· Skin reactions
· Arm swelling
· Sensory changes in the breast and arm
Side effects of Mastectomy
· Chest wall tightness, scar
· Phantom breast sensations
· Lymphedema
· Sensory changes
· Impaired ROM
Lymphedema
axillary nodes cannot return lymph back to central circulation, resulting in accumulation of lymph on soft tissue
lymphedema often accumulates in
arm, hand, breast
s/s of lymphedema
· Patient may have heaviness, impaired motor function, numbness and paresthesia of the fingers
when should women undergo regular screening mammography
starting at age 45 then annually after that
predignosis tests for breast cancer
· Mammography
· Ultrasound
· Breast MRI
· Biopsy