Topic 7: IBD Ulcerative Colitis & Chrons Flashcards
Inflammatory bowel disease
autoimmune disease; chronic inflammation of the GI tract characterized by periods of remission interspersed with periods of exacerbation
Ulcerative colitis
usually limited to the colon
Crohn’s
can involve any segment of the GI tract
Clinical Manifestations UC
· Teens to mid-30s. After 60
· Severe/constant abdominal pain
· Diarrhea (10-20 STOOLS A DAY)
· Fever during acute attacks
· Rectal bleeding
· Tenesmus (cramping rectal pain)
· Pseudopolyps
Clinical Manifestations Crohn’s
· Teens to mid-30s. After 60
· Cramping abdominal pain
· Diarrhea
· Fever
· Malabsorption and nutritional deficiencies
· Weight loss may be severe
Cobblestoning of mucosa
diagnostic studies for UC and crohns
· CBC, erythrocyte sedimentation rate
· Serum chemistries
· Testing of stool for occult blood and infection
· Capsule endoscopy
· Radiologic studies with barium contrast
· Sigmoidoscopy and/or colonoscopy with biopsy
Colonoscopy
when testing stool and occult blood, what is being looked for
looking for blood, pus, and mucous
acute care
· Focus on hemodynamic stability, pain control, fluid and electrolyte balance, and nutritional support.
· I&Os
· Monitor number and appearance of stools
· Assess presence of blood in stools and emesis
· Give IV fluids, electrolytes, analgesics, and anti-inflammatory drugs
· Monitor electrolytes, CBC, and VS
· Help patient stay clean, dry, and free of odor until the diarrhea is under control
· Perianal skin care using plain water (no harsh soap) and barrier creams
· Assess abdomen, including bowel sound
nutritional therapy for acute exacerbations
liquid enteral feedings are preferred
o High in calories and nutrients
o Lactose-free
o Easily absorbed
when it is acceptable to eat non liquid enteral feedings, what does diet therapy look like
· Regular foods are reintroduced gradually
· Lower the intake amount of fiber
patient teaching for IBD
· Importance of rest and diet management
· Perianal care
· Drug action and side effects
· Symptoms of recurrence of disease
· When to seek medical care
· Ways to reduce stress
Quit smoking
medications for IBD
Aminosalicylates (5-aminto salicylic acid)
Antimicrobials
Corticosteroids
Immunosuppressants
Biologic and targeted therapy (TNF and Integrin receptor antagonists)
corticosteroids
· Decrease inflammation
· Used to achieve remission
· Helpful for acute flare-ups
immunosuppressants
· Suppress immune response
· Maintain remission after corticosteroid induction therapy
· Require regular CBC monitoring