Test 2: Encompassing Terms Flashcards
Parts/functions of the motor system
Corticospinal tract: info from brain to body
Basal ganglia: motor subroutines
Cerebellum: modulates motor plans
Motor vs. sensory tracts
Motor: LMN to UMN. Corticospinal & corticobulbar.
Sensory: Afferent neuron, ascending tract, SS cortex. Spinothalamic & DCML.
Endogenous vs. Exogenous pain control
Endogenous: spinal cord gate, RFA (endorphins)
Exogenous: NSAIDs & Opiates
White matter vs. Grey matter
White: transmisssion, peripheral info.
Grey: central “H.” Neuron cell bodies, glial cell bodies.
Dorsal root ganglion
Cluster of neurons found only on dorsal roots.
Spinal rami
Dorsal: deep back muscles, z-joints
Ventral: everything else
Defn. of plexus, types in body
Anterior rami merge together to form a network called a “plexus.” Cervical (C1-C4), brachial (C5-T1), lumbosacral (L2-S4)
Lateral horn
Carries ONLY sympathetic info, only found in thoracic region
Draw a full brachial plexus.
google it girl
Memory structures in the limbic system
Hippocampal formation (A = dentate gyrus, E = subiculum), anterior thalamus, hypothalamus (mamillary bodies)
Emotional/behavioral structures in the limbic system
Amygdala, dorsomedial thalamus, hypothalamus (ANS nuclei)
Cingulate lobe
Cingulate gyrus + parahippocampal gyrus. Responsible for both memory and emotion/behavior, connections, reality check.
Amygdala
Analyses anger and fear expressions, provides output for the thalamus –> SNS
Mammillary bodies
Thalamic relay, recollective memory, behavioral reactions.
Hippocampus
Who, what, where, when. Long-term memory, output to cortex via fornix.
Episodic memory
Medial temporal lobe. (thalamus, amygdala, hippocampus = papez circuit)
Semantic memory
Neocortex (auditory, somatosensory, visual cortex)
Procedural memory
Muscle memory: cerebellum & basal nuclei.
Feeding, Sexual, Motivation
Feeding: activate hypothalamic nuclei
Sexual: increase oxytocin from post. pituitary gland
Motivation: increase dopamine
Somatic motor system
Voluntary controlm one neuron from CNS to effort. Ach is the only neurotransmitter, only innervates skeletal muscle.
Autonomic motor system
Two neurons between CNS and effector. Ach only at first neuron, Ach/E/NE at second, innervates cardiac, smooth, glandular tissue.
Only sympathetic/sympathetic innervation…
Sympathetic: sweat glands, visceral arterioles, radial muscle.
Parasympathetic: Iris sphincter
Sympathetic output systems
Short preganglionic neuron, Ach used in ganglia, called nicotinic receptors. NE is used on effector (adrenergic receptors)
Parasympathetic output systems
Long preganglionic neuron, Ach used in ganglia, called nicotinic receptors, Ach used on effector (muscarinic receptor)
Cholinergic receptors.
Found in both ganglia, postganglionic parasympathetic effectors. 2 types: muscarinic (found on organs), nicotinic (found on ganglia). Short period of activation (Ach breaks down quick).
Adrenergic receptors
Found only on sympathetic postganglionic target organs. 2 types: alpha (contract), beta (contract except cardiac). Long activation period.
Adrenergic Receptor subtypes
a1 = contract smooth muscle
a2 = clotting
b1 = contract heart muscle
b2 = relax bronchioles, uterus, arterioles
b3 = increase lipolysis
Adrenergic drugs
Beta blockers = for tachycardia, hypertension
Beta agonists = for asthma
HPA Axis
Overtakes after stress response. Includes hypothalamus, pituitary gland, adrenal gland.
Layers of connective tissue on muscle
Endomysium, perimysium, fascicle, epimysium
Cross bridge cycling
When Ca2+ is added into a sarcomere, troponin (molecule on actin) bind and pulls tropomyosin (rope-like molecule on actin) away from the binding sites, allowing actin-myosin interactions. ATP then breaks the actin-myosin bond, cycle starts again.
Sarcolemma
Pores on muscle, allow action potential to enter and propogate down T-tubules, through terminal cisternae, then sarcoplasmic reticulum.
Receptors in sarcoplasmic reticulum
DHP (cork) and Ryanodine receptors. They open up concentration gradient from calcium storage in SR –> actin/myosin interaction.
Motor unit
One motor neuron & all the muscle fibers it innervates
Types of skeletal muscle fiber types in order of fast-to-slow recruitment.
Slow oxidative, fast oxidative-glycolytic, fast glycolytic
Factors of muscle force production
Muscle length, AP frequency, motor unit size, fiber types
3 types of joints, cartilage they have (if app.) and their sub-classes (if app.)
Fibrous (none)
Cartilaginous (hyaline & fibrocartilage). Synchondroses & symphyses.
Synovial (hyaline). Pivot, plane, hinge, ball & socket, condyloid, saddle.
4 factors of stability/motion in joints.
Shape/arrangement of articulating surfaces, tone/arrangement of surrounding muscles, ligaments crossing the joint, hormones.