T. Urine Flashcards
What are the primary functions of the Kidneys?
- filter waste products from blood stream
- extcrete metabolic waste
- maintain electorlyte levels
- maintain acid base balance
What are the secondary regulator functions of the kidneys
- regulate bp
- regulare bone density and erypopoesis and produce erythopotein
- activate vitamin D
- procude/secrete renin
Urinary tract infection
- Include cystitis, urethritis, pyelonephritis
- E.Coli is the most common pathogen
- Predisposing factors include tumours, stones, urinary retention, foreign bodies functional disorders and factors compromising immune response
- Most common bacterial infections in women
cystitis
- Inflammation of the urinary bladder
- Characterized by pain, urgency, frequency, hematuria
- Interstitial cystitis
urethritis
- Inflammation of the urethra
* Causes bacterial or viral infection
pyelonephritis
Inflammation of the renal parenchyma and the collecting system usually caused by infection.
Upper or lower urinary tract infection
upper = renal pelvis/gerdle, ureters and kidneys lower = involve the urethra and bladder
Complicated or uncomplicated UTI
Complicated
(happens with catherters or diabetes) or
Male
Or Female who’sIs postmenopausal;
Is pregnant;
Has an anatomically or functionally abnormal urinary tract (for example, bladder outlet obstruction, a colovesical fistula, hydronephrosis, neurogenic bladder, stone disease, or vesicoureteral reflux);
Has a foreign body within her urinary tract (for example, a catheter or a stent); OR
Has one or more comorbidities or conditions requiring special consideration (for example, diabetes, immunodeficiency, renal insufficiency, or a prior organ transplant)
Uncomplicated
(normal UTI, and usually only involve the bladder.)
Is female;
Is healthy;
Is premenopausal;
Is not pregnant; AND
Has an anatomically and functionally normal urinary tract
Upper/Lower UTI
Upper: kidneys/ureter
Lower: bladder/urthrea
Acute Pyelonephritis
- Inflammation of the renal parenchyma
- Most common cause I bacterial infection, but fungi, protozoa or viruses can infect the kidney.
- treat with antibiotics
Chronic Pyelonephritis
- a kidney that has become shrunken and has lost function owing to scarring or fibrosis.
- It usually occurs as the outcome of recurring infections involving the upper urinary tract
- Can lead to end stage renal disease of both kidneys are involved.
- In chronic pyelonephritis the kidneys become small, atrophic, and shrunken and lose function as a result of fibrosis (scarring).
Urethra diverticula
The result of obstruction and subsequent rupture of the periurethral glands into the urethral lumen with epithelialization (regrowth of tissue) over the opening of the resulting periurethral cavity
a rare condition where an unwanted pocket or sac forms along the urethra, the tube that carries urine (pee) out of the body.
Renal tuberculosis
- caseous lesions that may necrose and destroy functioning renal parenchyma
- it is usually secondary to TB of the lung.
Glomerulonephritis
- An immune related inflammation of the glomeruli.
* Proteinuria, hematuria, decreased urine production and edema.
Acute Poststreptococcal Glomerulonephritis
- Occurs 5 – 21 days after an infection of the pharynx or skin by nephrotoxic strains of GrouP A B-hemolitic streptococci.
- n immunologic response of the kidney to infection, characterized by the sudden appearance of edema, hematuria, proteinuria and hypertension
Goodpasture’s Syndrome
- autoimmune disease characterized by circulating antibodies against glomerular and alveolar basement membrane.
- your body mistakenly makes antibodies that attack the lungs and kidneys
- Primary target organ is the kidney, but the lungs are also involved
Rapidy progressive glomerulonephritis
- Glomerular disease associated with rapid, progressive loss of renal function over days to weeks
- Renal failure may occur within weeks to months, in contrast to chronic glomerulonephritis, in which it develops insidiously and progresses over many years
proteinuria
abnormal amounts of protein in urine
hematuria
blod in urine
Chronic glomerulonephritis
• A syndrome that reflects the end stage of glomerular inflammatory disease
Nephrotic syndrome
- a kidney disorder that causes your body to pass too much protein in your urine.
- Nephrotic syndrome is usually caused by damage to the clusters of small blood vessels in your kidneys that filter waste and excess water from your blood
- Occurs when the glomerulus is excessively permeable to plasma protein - proteinuria – which leads to low plasma albumin and tissue edema
Obstructive uropathies
Includes any anatomical or functional condition that blocks or impedes the flow of urine.
Congenital or acquired.
Urinary tract calculi
- kidney stones
* Stones (calculi) are hard masses that form in the urinary tract and may cause pai
Nephrolithiasis
Major categories of Stones
Calcium phosphate, calcium oxalate, uric acid, crystine struvite (magnesium-ammonium phosphate)
crystals precipitate to form stones which lodge within the urinary system