T. Heart Failure Flashcards
Preload
venous return that build during diastole
is the amount of ventricular stretch at the end of diastole. Think of it as the heart loading up for the next big squeeze of the ventricles during systole. Some people remember this by using an analogy of a balloon – blow air into the balloon and it stretches; the more air you blow in, the greater the stretch.
the stretch of myocardium or end-diastolic volume of the ventricles and most frequently refers to the volume in a ventricle just before the start of systole.
Contractility
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Afterload
the opposing pressure the ventricles have to generate to get the aortic values open
the amount of resistance the heart must overcome to open the aortic valve and push the blood volume out into the systemic circulation. If you think about the balloon analogy, afterload is represented by the knot at the end of the balloon. To get the air out, the balloon must work against that knot.
Heart Failure
- An abnormal condition involving impaired cardiac pumping/filling
- Heart is unable to produce an adequate cardiac output (CO) to meet metabolic needs (inadequate stroke volume and cardiac output)
- not a disease but a “syndrome.”
Ejection Fraction
- How much blood a ventricle pumps out with each contraction.
- An ejection fraction of 60 percent means that 60 percent of the total amount of blood in the left ventricle is pushed out with each heartbeat.
- Normal is 60-80%
- Under 40% may be evidence of heart failure orcardiomyopathy
Heart failure with preserved ejection fraction
Impaired ability of the ventricles to relax and fill during diastole, resulting in decreased stroke volume and CO
occurs when the lower left chamber (left ventricle) is not able to fill properly with blood during the diastolic (filling) phase
Mixed heart failure
Poor systolic function is further compromised by dilated left ventricular walls that are unable to relax.
Biventricular failure
Both ventricles may be dilated and have poor filling and emptying capacity.
Diastolic heart failure
- Heart has thick walls, so the ventricles cannot relax and fill during diastole. Decreased filling results in decreased stroke volume and CO, as well as venous engorgement in both the pulmonary and systemic vascular systems.
- L. ventricle loses ability to relax, muscle too stif and heart can’t fill blood in resting eriod between each beat.
Systolic heart failure
- Heart has thin walls, so the left ventricle cannot pump effectively.
- L. ventricle loses ability to contract, heart can’t pump with enough force to push it through too much afterload
Neurohormonal responses
RAAS
• compensatory mechanism for heart failure
• kidneys release reinin –> angiotensinogen –>angiotensin I–> angiotensin II–> release aldosterone (sodium and water retention)
• secretes Antidiuretic hormone (ADH)
>vasoconstriction.
>increase in cardiac contractility.
>Hypertrophy.
Response is known as the renin–angiotensin–aldosterone system (RAAS).
Dilation
- Compensatory mechanism
- Enlargement of the chambers of the heart that occurs when pressure in the left ventricle is elevated.
- Initially an adaptive mechanism
- Eventually this mechanism becomes inadequate, and CO decreases
Hypertrophy
- Compensatory mechanism
- Increase in muscle mass and cardiac wall thickness in response to chronic dilation
- Over time the thickening tissue needs more oxygen and has poor contractility since there’s no room
Counterregulatory processes
• Released in response to increase in atrial volume and ventricular pressure
• Promote venous and arterial vasodilation, reducing preload and afterload
• Released natriuretic peptides:
– atrial natriuretic peptide (ANP),
– b-type natriuretic peptide (BNP)
Left-sided Heart Failure
- Left ventricle often fails first
- Blood backs up into left atrium & pulmonary veins
- Causes pulmonary congestion & edema
- Patient has SOB and fluid accululation. Lungs sound wet. Cap refil impaired, edema,
- 2 types systolic and diastolic failure