Système gastro-intestinal Flashcards

1
Q

IPP-Caractéristiques

A
  • Prodrogue acidosensibles
  • Inihibiteur irréversibles
  • Efficace sur la production acide basale et stimulée
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2
Q

IPP-Indication

A
  • Traitement et prévention d’ulcère
  • Symptômes de reflux et d’oesophagite de reflux
  • Syndrome de Zolliger-Ellison
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3
Q

IPP-Effets indésirables

A
  • Troubles gastro-intestinales
  • Diminution Réabsorption de VIT B12 et du fer
  • Hypergastrinémie
  • Risque accru d’infection gastro-intestinale et respiratoire
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4
Q

IPP-Interaction

A

Clopidogrel ? (CYP 2C19)

–> respecter un intervalle de 12h entre la prise des 2 médoc

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5
Q

Anti-histaminiques H2-Noms

A

Ranitidine

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6
Q

Ranitidine-Mode d’action

A

Antagoniste des récepteurs H2

Efficaces sur la production acide basale ( prise le soir)

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7
Q

Ranitidine-Indication

A
  • Traitement et prévention des ulcères
  • Symptômes de reflux
  • Dyspepsie, gastrite, pyrosis
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8
Q

Ranitidine-Effet secondaire

A
  • Trouble gastro-intestinales

- Douleurs musculaires

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9
Q

Anti-acides-Noms

A

Gaviscon
Maalox
Rennie

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10
Q

IPP-Noms

A
  • Lansoprazole
  • Oméprazole
  • Esoméprazole
  • Pantoprazole
  • Rabéprazole

-> «prazole»

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11
Q

Anti-acides - Mode d’action

A

Base faibles + HCl -> sels + eau

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12
Q

Anti-acides - Indication

A

Dyspepsie
Gastrite
Pyrosis

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13
Q

Anti-acides - EI

A

Mg -> diarrhée
Ca, Al -> constipation
Carbonates -> flatulences

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14
Q

Misopristol - Mode d’action

A

Analogue de la PGE1
Diminution de la production acide
Augmentation de la sécrétion de mucus et bicarbonate

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15
Q

Misoprostol - Indication

A

Prévention des ulcères en cas de prises d’AINS

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16
Q

Misoprostol - EI

A

Troubles gastro-intestinaux

17
Q

Misoprostol - CI

A

Grossesse