Synaptic transmission Flashcards
Fast signaling neurotransmitters (2)
Glutamate
GABA
Slow signaling neurotransmitters (4)
Dopamine
Noradrenaline (Norepinephrine)
Seratonin
Acetycholine
(High/low) Na+ concentration outside cell
High
(High/low) K+ concentration outside cell
Low
At rest, cell membrane is much more permeable to ___ than ___
K+
Na+
Round clear vesicles
glutamate
Has electron-dense post-synaptic density
Glutamate
Flattened, clear vesicles
GABA
Has inconspicuous post-synaptic density
GABA
Round electron-dense vesicles
Bioagenic amines
Has variable post-synaptic density
Bioagenic amines
___ opens Na+ channels
Glutamate
Excitatory
___ opens Cl- channels
GABA
Inhibitory
Low molecular weight amino acids
Glutamate
GABA
Aspartate (excitatory)
Glycine (inhibitory)
Most widely used neurotransmitters in brain
Low molecular weight AA
Present in cells throughout body at high levels
Low molecular weight AA
Stiff person syndrome
Functional impairment of spinal interneurons due to autoimmune antibodies directed against GAD (synthesizes GABA)
