spondyarthropathies

Question 1

What is the gene involved in 90% Spondyloarthritis patients?

Answer 1

HLA-B27

Question 2

Ankylosing spondylitis mostly affects the ____, particularly at the ______ joint

Answer 2

spine

sacroiliac

Question 3

Ankylosing Spondylitis associated pain improves at rest (T/F)

Answer 3

False

pain lessened with exercise

Question 4

How is Ankylosing Spondylitis diagnosed?

Answer 4

Examination

• Occipit to wall
• chest expansion
• Schober test (modified)

Bloods
-inflammatory markers (CRP, PV, ESR)

X-rays:

• reduced joint space
• subchondral sclerosis

MRI

• bone marrow oedema
• enthesitis

Question 5

What is the treatment for Anklyosing Spondylitis?

Answer 5

-physiotherapy

• NSAIDs
• Methotrexate
• Anti-TNF (Infliximab)

-Anti-IL17 (Secukinumab)

Question 6

What is the cause of Reactive Arthritis?

Answer 6

Infection

-induces systemic illness

Question 7

Enteropathic Arthritis is associated with ___

Answer 7

IBD

-Crohn’s, Ulcerative Colitis

Question 8

NSAIDs should be used for Enteropathic Arthritis (T/F)

Answer 8

False

-can exacerbate IBD

Question 9

Psoriatic arthritis affects joints asymmetrically (T/F).

Answer 9

True

Question 10

Other than rash and arthritis, what other symptoms may be present in psoriasis?

Answer 10

Nail pitting and lifting off the nail bed (onycholysis)