Microbiology Flashcards
What is Osteomyelitis?
Inflammation of bone and medullary cavity
What is the gold standard diagnostic test for osteomyelitis?
Bone biopsy
-microbiological confirmation of pathogen
Staph aureus is a Gram +ve, coagulase negative coccus (T/F)
False
Staph aureus is coagulase +ve
Staph epidermidis likes to live on….
metal and plastic
-prosthetics, meshes, etc
What is the treatment for Staph aureus? What is the alternative for penicillin-allergic patients?
Flucloxacilin
Vancomycin
Antibiotic for Gram -ves?
Gentamycin / Doxycycline
Antibiotic for anaerobes?
Metronidazole
What pathogens are associated with Sickle cell osteomyelitis?
Salmonella
Staph areus
What is the bacterium associated with vertebral osteomyelits outwith the UK?
TB
Skeletal tuberculosis is highly infectious (T/F)
False
not infectious
Prosthetic joint infections are associated with what coagulase negative bacterium?
Staphylococcus epidermidis
What pathogens cause septic arthrits?
-Staph aureus
- Streptococci
- Staph epidermidis (prosthetics)
- Neiserria gonorrheae (sexually active, multiple joints involved)
What non-infectious process can mimic septic arthritis’ symptoms?
gout
What is the 1st line treatment of septic arthritis?
Flucloxacillin
Vancomycin if MRSA
Pyomyositis resolves with antibiotic treatment (T/F)
False
Debridement is essential to remove puss/necrotic tissue first
