MSK histology

Question 1

Striated, unbrached, multinucleate, with nuclei at the fibre periphery are characteristics of ______ muscle.

Answer 1

skeletal

Question 2

What is the epimysium?

Answer 2

connective tissue that surrounds the whole muscle

Question 3

The connective tissue around a single fascicle is the _____, whereas the connective tissue around a single muscle fibre is the _____

Answer 3

fascicle - perimysium

muscle fibre - endomysium

Question 4

A muscle fibre bundle bound by perimysium connective tissue describes…

Answer 4

a fascicle

Question 5

Describe the levels of skeletal muscle organisation:

Answer 5

1. sarcomere
2. myofibril
3. muscle fibre
4. fascicle
5. skeletal muscle

Question 6

__ ______ represents the attachment point for myosin/thick filaments

Answer 6

M line

Question 7

Slow contracting fibres that depend on oxidative metabolism, are abundant in mitochondria and myoglobin and produce low force are called…

Answer 7

Type I fibres

‘slow twitch’

Question 8

Intermediate fibres, relatively fast contracting are…

Answer 8

Type IIA

‘fast oxidative fibres’

Question 9

Fast contracting fibres depending on anaerobic metabolsim, have fewer mitochondria and less moglobin, fatigue easily and produce large force …

Answer 9

Type IIB fibres

‘fast glycolytic fibres’

Question 10

Cartilage is highly vascularised (T/F)

Answer 10

False

Avascular

Question 11

What cells are found in cartilage?

Answer 11

Chondrocytes

Question 12

The lacuna is …

Answer 12

extracellular matrix occupied by chondrocytes

Question 13

What are the components of the Extracellular Matrix in cartilage?

Answer 13

Water (75%)
Type II collagen
Proteoglycan aggregates

Question 14

_____ bone is formed of a fine meshwork found in the epiphyses of bones.

Answer 14

Cancellous / trabecular

Question 15

The outer dense shell is the ____ bone, found in the diaphysis.

Answer 15

cortical bone

Question 16

Layers of insterstitial lamellae in the cortical bone change direction witch each layer, providing it with tensile strength (T/F).

Answer 16

yup

Question 17

Haversian Canals contain the osteonal _____

Answer 17

artery, vein and nerves

Question 18

Osteocytes in lacunae access resources via ____, which connect them to _____

Answer 18

projections (dendrites) which connect them to the blood vessels in Haversian canals

Question 19

What is the function of osteoclasts?

Answer 19

Bone resorption -

‘destruction’

Question 20

What is the function of osteoblasts?

Answer 20

bone formation

Question 21

What is the type of weak bone initially laid down following fracture (or during development)?

Answer 21

Woven bone

Question 22

What is an osteon?

Answer 22

cylidrical units with cortical bone composed of layers of collagen fibres, with a central Harvesian canal containing blood vessels and nerves

Question 23

What eventually happens to Woven bone?

Answer 23

It becomes remodelled into lamellar bone by osteoclasts and osteobasts