SPECONLEC_S1_L3 - P14-P29 Flashcards
Reaction to drugs is always the same as in younger
age groups t or f
f, Reaction to drugs not always the same as in younger age groups
MEDICATION METABOLISM: Adverse effects
more frequent and may be more severe t or f
t
adipose tissue causes larger
volume of distribution for fat-soluble drugs
inc
increased adipose tissue leads to _
prolonged biologic
half-life
More diffused in the body for meds means
more fat stored in the body
Decreased total body water means that the meds are_
decreased volume of distribution of water-soluble
Since the hydration is low, you would expect
(inc or decrease) volume of water
decrease
low hydration means there will be
concnetration of drugs
higher
more concentrated drug means _
more potency and adverse effects of drug
Hepatic drug clearance decreased up to what percent
30%
Renal clearance decreased up to what percemt
50%
decrease in renal and heaptic clearance means that _
longer duration of drug in the body
GAIT: speed,
double limb support, stride length
dec, inc, shorter
gait is affected by:
vision,
cognition,
motor control,
balance,
peripheral sensation,
strength,
joint health,
metabolic demands
predictor of survival, possibly a biomarker of
health status in older adults
Gait speed
If able to walk faster > what are the chances of survival
more chances of survival
If slower than normal >what can be the prognosis
poor prognosis
Indicators of gait speed: what are the OMTs to be used
6-minute walk test
(6MWT)
gait speed that has relatively good function
1.0 m/sec
gait speed for predicitng median life expectancy for age &
sex
0.8m/sec
CONDITIONS & DISEASES IN THE ELDERLY (16)
frailty
disuse and immobilization
falls
osteoarthritis
osteopenia and osteoporosis
hip fx
stroke
TBI
SCI
dementia
delirium
normal pressure hydrocephalus
parkinson disease
amputation
cancer
polypharmacy
Age and disease-related loss of adaptation, such that
events of previously minor stress result in disproportionate
biomedical and social consequences
FRAILTY
Clinical Syndrome for frailty (5) (US WSL)
○ Unintentional weight loss of at least 10 lb over the
past year
○ Self-reported-exhaustion
○ Weakness (grip strength)
○ Slow walking speed
○ Low physical activity
Clinical Syndrome should have how many to be considered
as frailty
3 or more
frailty can be attributable to _ _ _
aging, diseases, and comorbidity
Exacerbates decline in body systems
DISUSE AND IMMOBILIZATION
DISUSE AND IMMOBILIZATION is a combination of
_ + _
inactivity, lack of mechanical loading
Combination of inactivity and lack of mechanical loading
lead to _
negative effects of bed rest
what will pt lose if he is predosposed to
disuse and immobilization
● Loss of muscle mass
● Loss of strength and power
disusue and immobilization:
muscle insulin resistance
increased
disusue and immobilization:
bone loss
increased
disusue and immobilization:
pulmonary function and exercise capacity
decreased
Inability of blood vessels to adapt
OH
there is _ venous return in OH
low
Impaired balance and coordination for disuse and immob
t or f
t
Increased/decreased risk for pressure ulcers for disuse
increased
Low nutrition can contribute to pressure ulcers t or f
t
Immobility from bed rest, predictor of decline in ADLs,
institutionalization & death in hospitalized older patients
DISUSE AND IMMOBILIZATION