Small And Large Intestines Flashcards

1
Q

What are the 3 segments the small intestine splits into

A

Duodenum
Jejunum
Ileum

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2
Q

What is the small intestine lined with

A

Glycocalyx

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3
Q

What are the 6 cells in the small intestine

A

Enterocytes
Goblet cells
Enteroendocrine cells
Paneth cells
Micro fold cells
Stem cells

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4
Q

What is the function of enterocyte cells

A

Express catabolic enzymes role in absorption

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5
Q

What do goblet cells do

A

Secrete mucus

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6
Q

What do enteroendocrine cells do

A

Gastrointestinal hormone secretion
Secretin, pancreozymin, enterglucagon
Sensory - synapsing with afferent nerves

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7
Q

What do paneth cells do

A

Synthesis of antimicrobial peptides regulates intestinal microflora

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8
Q

What do microfold cells do

A

Antigen presenting cells - present antigens to peyers patches

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9
Q

What do stem cells do

A

Self renew by dividing and differentiate into the specialised cells of the intestinal epithelium

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10
Q

What 3 factors decrease gastric emptying

A

High fat content
Low pH
Hypertonicity (high osmolarity)

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11
Q

What does bile do

A

Emulsifies fats assisting in their absorption

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12
Q

What is stimulated to release bile from the gall bladder into the duodenum

A

Stimulation of cholecystokinin

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13
Q

What is the pancreases endocrine function

A

Insulin and glucagon

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14
Q

What is the pancreases exocrine function

A

Pancreatic juices

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15
Q

What are the 4 pancreatic enzymes

A

A amylase
Lipase
Nucleases
Proteolytic enzymes e.g. proteases and peptidases

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16
Q

What are plicae circulares

A

Circular folds of mucosa evident in the jejunum

17
Q

What does the ileum mainly absorb

A

Vitamin B12 and bile salts

18
Q

Where are peyers patches found

A

Within lamina propria and submucosa

19
Q

What is carboxypeptidase

A

A protease enzyme that hydrolyses (cleaves) a peptide bond specifically at the C-terminal of a protein or peptide

20
Q

What is aminopeptidase

A

Cleaves peptide bonds at the amino terminal of a protein

21
Q

What is lactose intolerance

A

Insufficient levels of lactose - enzyme which hydrolyses lactose to glucose and galactose

22
Q

What are the 5 main functions of the large intestine

A

Reabsorption of water
Reabsorption of bile salts
Absorption of vitamins produced by bacteria
Compaction of intestinal contents to produce faeces
Storage of faeces prior to defaecation

23
Q

Which intestine has a thinner wall

A

Large intestine

24
Q

What is the large intestines walls made of

A

Small sacs called Haustra which permit expansion and elongation of the colon

25
What are the 3 section of the large intestine
Ascending Transverse Descending
26
What is the caecum
Very first part of the large intestine
27
What is the appendix thought to be involved in
Gut microbiota helping to replenish colon with microbiota if it becomes depleted during an immune reaction
28
What are the 3 synthesis of vitamins by intestinal bacteria
Vitamin K - clotting factors Biotin - glucose metabolism Pantothenic acid - vitamin B5
29
What does bacteria convert bilirubin to
Stercobilinogen - responsible for the pigmentation of faeces
30
What does bacteria in the the large intestine break down
Peptides in faeces and generate gases - ammonia and hydrogen sulphide
31
What does the anal canal contain
Small longitudinal folds
32
What is the anus lined with
Keratinised squamous epithelium