Oesophagus And Stomach Flashcards

1
Q

What are 5 functions of the GIT

A

Ingestion
Digestion
Absorption
Elimination
Protection

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2
Q

What type of epithelium is mucosa made of

A

Stratified squamous epithelium

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3
Q

What is the function of mucosa

A

Provides protection from abrasive foods and liquids

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4
Q

What does the submucosal and mucosal glands do

A

Secrete protective/lubricating mucous

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5
Q

What are the 3 functions of the cardiac and pyloric glands

A

Primary mucus secreting
Cardiac glands have coiled ends
Pyloric glands are highly branched

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6
Q

What is the intrinsic innervation of the control of the GIT

A

Myenteric and submucosal plexuses

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7
Q

What are interstitial cells of cajal

A

Pacemakers for peristaltic action of the gut and sit in the myenteric and submucosal plexuses

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8
Q

How does the GIT communicate with the brain

A

Via nerve which function as the gut brain axis sensory neurons with cell bodies in dorsal root ganglia or in parasympathetic relay ganglia - there is no region in the brain exclusively dedicated to gut functions

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9
Q

What are the 2 intrinsic enteric nervous system controls

A

Myenteric (Auerbachs)
Meissners

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10
Q

What are the 2 extrinsic nervous systems controls

A

Parasympathetic
Sympathetic

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11
Q

What does the submucosal nerve plexus do

A

Regulates glandular and mucosal secretions

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12
Q

What does the myenteric plexus do

A

Controls gut wall contraction and gut motility

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13
Q

What does the parasympathetic control do

A

Enhances gut motility and secretion

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14
Q

What does the sympathetic control do

A

Inhibits gut motility and secretion

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15
Q

What are enterochromaffin like (ECL cells)

A

Distinctive type of neuroendocrine cell in the gastric mucosa underlying the epithelium
Synthesise and secrete histamine in response to stimulation by the hormone gastrin

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16
Q

What does cardia do

A

Mainly mucus secreting cells

17
Q

What does fundus do

A

Acid producing parietal cells
Pepsin producing chief cells

18
Q

What does pylorus do

A

Gastrin hormone production

19
Q

What are the 3 main phases of stomach digestion

A

Cephalic
Gastric
Intestinal (Basal)

20
Q

What is the stimulation for the cephalic phase

A

CNS responses to presentation of food enhances gastric gland secretion

21
Q

What is the inhibition of the cephalic phase

A

Loss of appetite satiety/depression

22
Q

What is the cephalic phase mediated by

A

The vagus nerve entirely reflex in origin

23
Q

What happens in the gastric phase

A

Food enters the stomach stretch activate pH increase peptides produced increase gastric gland secretion

24
Q

What 2 factors decrease gastrin secretion

A

If pH <2.0
Sympathetic response also decrease gastrin activity

25
Q

What happens in the intestinal phase

A

Chyme produced after stomach digestion enters duodenum enteric mucosa secretes gastrin stimulates secretion by gastric glands

26
Q

What 4 factors happen when the enterogastric reflex is triggered

A

Inhibits stimulation
Inhibits local reflexes
Controls gastric emptying
Stimulates sympathetic fibres to close pyloric sphincter