Session 5 MSK Flashcards
The neural tube contains the
Precursor cells of the nervous system
What happens in an 18 day embryo
- Influence of notochord
- Neural tube invaginate to form neural groove
- Neural folds fuse at midline
- Neural tube formed
What has happened by 24 day stage
Cephalon head and caudal tail ends of neural tube have closed
What happens from day 20 onwards-
paired Somites (primitive segments) appear
What happens by day 30
Embryo has approx 34-35 pairs of Somites that begin to differentiate as soon as they are formed
What happens during the 4th week after fertilisation
Each Somite differentiates into the sclerotome, (ventral- gives rise to vertebrae and ribs), dermatomyotome (dorsal and forms dermis via dermatomes) and muscle tissue via the myotomes
Dermatomyotomes develop in association with
A specific neural level of spinal cord and take nerve supply with them from neural tube as spinal nerve
Skin and muscle derived from a single dermatomyotome have a
Common spinal nerve supply
What is a dermatome
An area of skin supplied by a single spinal nerve
Landmarks of Foerster dermatome map
T4/T5- nipped
T10- umbilicus
L1- groin
What is a neuron
An electrically excitable cell that receives, processes and transmits information through chemical and electrical signals
Within the nerve, each axon is surrounded by a layer of connective tissue called
Endometrium
Structure within endoneurium
- Endonurial fliud
- Axons are bundled into fascicles and surrounded by perineurium connective tissue
- Fascicles grouped together and surrounded by epineurium
- Vasa nervorum
What is a spinal nerve
A mixed nerve that carries motor, sensory and autonomic signals between body and spinal cord
What does dorsal nerve root do
Transmits sensory fibres from the sensory receptors to the spinal cord, afferent
What does ventral nerve root do
Carried motor and autonomic fibres leaving spinal cord, efferent
Spinal nerves key points
31 pairs, numbered according to level of vertebral column they emerge from. Short and exist briefly as they pass through intervertebral foramen
Each vertebra is derived from
Parts of 2 adjacent Somites
Spinal cord runs through
Vertebral foramen, multiple vertebra foramina form spinal canal
Spinal nerves leave spinal canal through
Gaps between vertebrae knows as intervertebral foramina