SERONEGATIVE SPONDYLOARTHROPATHIES III

Question 1

what are some examples of GI diagnoses that have arthritis as extra intestinal manifestation?

Answer 1

inflammatory bowel disease like Crohn’s disease and ulcerative colitis

celiac diseases, bacterial infections of the gut

Question 2

epidemiology of ulcerative colitis and crohns disease?

Answer 2

patients with IBD have arthritis

males and females equally affected

children and adults are at risk for associated arthritis

Question 3

chronic inflammatory condition of the GI tract most commonly affecting the end of the small bowel and beginning of the colon

affects all layers of the bowel

Answer 3

crohns disease

Question 4

chronic inflammatory disease of the colon

usually effects the inner most lining of colon

Answer 4

ulcerative colitis

Question 5

pathogenesis for arthritis of inflammatory bowel disease?

Answer 5

unclear

both are familial
croons disease and ulcerative colitis

Question 6

clinical presentation for the arthritis of inflammatory bowel disease?

Answer 6

spinal arthritis involvement
asymptomatic sacroiliitis
enthesitis
peripheral arthritis 
-may be acute and remitting
-migratory joint inflammation
-asymmetric and oligoarticular
-largely lower extremity
-joint effusions
-usually nondestructive joint damage
peripheral arthritis
extra articular manifestations

Question 7

name this associated condition?

inflammation of the fat cells under the skin

tenderness, red nodules that are usually seen on both shins

Answer 7

erythema nodosum

Question 8

name this associated condition?

severe, painful, ulcerating skin reaction

tissue becomes necrotic resulting in ulcerations

will need wound care and potentially topical steroid

sites will start as small pink papules and progress to large ulcers

frequently associated with systemic disease

Answer 8

pyoderma gangrenosum

Question 9

labs for the arthritis of inflammatory bowel disease?

Answer 9

no specific test for IBD related arthritis

Question 10

radiographic for the arthritis of inflammatory bowel disease?

Answer 10

indistinguishable from AS

Question 11

diagnosis for the arthritis of inflammatory bowel disease?

Answer 11

careful history and clinical findings

-potentially spinal radiographs

Question 12

treatment for the arthritis of inflammatory bowel disease

Answer 12

treat the underlying IBD controlling the peripheral arthritis

caution with NSAIDs-GI side effects

DMARDs

Biologics