NAIL DISORDERS HIGH YIELD Flashcards
so the proximal nail fold has what two skin surfaces?
dorsal and ventral skin surfaces
what is significant about the plantar digital artery?
dominant vessel
important components of the nail bed?
un-encapsulated nerve balls
vater-pacinian pressure receptors
meissners corpuscle
what is important to note about the dorsal portion of the nail matrix?
ventral skin surface of proximal nail fold
forms the thin dorsal surface of the nail plate
what is to note of the distal seal of the hyponycium protecting the nail bed from infection?
onychodermal band
when does the nail matrix begin in utero?
few melanocytes are derived from the?
9-10 weeks
neural crest
onychocytes are closely packed, adherent, interdicting cells that are normally clear and translucent, so what should we note also about the many intercellular links and tight junctions?
frequent gap junctions
- intercellular channels
- more permeable to polar solutions than is skin
the nail plate is composed of? and grows at a rate of _____?
alpha keratin protein
0.1 mm per day or 3 mm per month
pedal nail plates average how long per month?
the toe nail completes turn over cycle how many months?
1 mm
12-18 months, decreases with age
what determines the thickness of the nail plate?
length of the matrix
nail plate is more permeable to?
polar solutions like water
skin is more permeable to?
non polar compounds like oils
what determines nail hardness?
this does not contribute to nail hardness?
moisture content
what is a nail unit anitmicrobial peptide?
cathelicidin
-leads to decreased levels in atopic eczema patients
name an example of primary IGTNs?
hereditary onychocryptosis