Sarin

Question 1

What is Serin

Answer 1

An Irreversible cholinesterase inhibitor

Question 2

what is bad about nerve agents

Answer 2

extremely toxic and have a very rapid effect

Question 3

The route of entry of the nerve agent is critical to both the speed and type of symptoms developed.
Generally, if the agent is absorbed via the respiratory system how quick is the response

Answer 3

Quick. The Quickest.

Question 4

What is the slowest response and why

Answer 4

Poisoning takes longer when the nerve agent enters the body through the skin, as although the Nerve agents are generally fat-soluble and can penetrate the skin it takes time before the poison reaches the deeper blood vessels.

Question 5

When Sarin enters the body through the skin, how long until you get the first symptoms?

Answer 5

20-30 minutes after the initial exposure but the poisoning process may be rapid if the total dose of nerve agent is high.

Question 6

What do Nerve agents inhibit

Answer 6

cholinesterases

Question 7

What happens when the cholinesterases are inhibited?

Answer 7

causes the acetylcholine concentration to increase causing potentiation of the effect of acetylcholine at cholinergic synapses

Question 8

What are Cholinesterase inhibitors used for in the clinic

Answer 8

Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system