Fluoxetine Flashcards
1
Q
what is fluoxetine
A
A selective serotonin reuptake inhibitor
2
Q
what is fluoxetine used to treat
A
to treat depression, bulimia nervosa, premenstrual dysphoric disorder, panic disorder and post-traumatic stress
3
Q
what is fluoxetine metabolized into
A
norfluoxetine
4
Q
mechanism of action of fluoxetine
A
Its mechanism of action is the inhibition of the reuptake or serotonin at the serotonin reuptake pump of the neuronal membrane, enhancing the actions of serotonin on 5HT1A autoreceptors
5
Q
difference between SSRIs and tricyclic antidepressant drugs?
A
SSRIs bind with significantly less affinity to histamine, acetylcholine, and norepinephrine receptors than tricyclic antidepressant drugs.
