Atracurium

Question 1

what is atracurim

Answer 1

A competitive cholinergic receptor anatagonist. a nondepolarizing skeletal muscle relaxant

Question 2

what is the mode of action of the atracurium

Answer 2

Its mode of action is it antagonizes the neurotransmitter action of acetylcholine by binding competitively with cholinergic receptor sites on the motor end-plate. This leads to muscle relaxation.

Question 3

what does the duration of the neuromuscular block

Answer 3

is between 1/3 to ½ of d-tubocurarine, metocurine, and pancuronium at initially equipotent doses

Question 4

what effect does repeated adminstration of maintainance does of Atracurium

Answer 4

has no cumulative effect on the duration of neuromuscular block if recovery is allowed to begin prior to repeat dosing

Question 5

does the time needed to recover from repeat doses does change with additional doses?

Answer 5

no

Question 6

Can repeat doses can, therefore, be administered at relatively regular intervals with predictable results?

Answer 6

yes

Question 7

what is the action of atracurium reversed by?

Answer 7

The action of Atracium is reversed by acetylcholinesterase inhibitors such as neostigmine, edrophonium, and pyridostigmine