Muscarine Flashcards
1
Q
what is muscarine?
A
Muscarinic cholinergic receptor agonist
2
Q
how does muscarine mimic the effects of acetylcholine
A
by binding the muscarinic acetylcholine receptors
3
Q
what are the 5 different types of muscarinic receptors?
A
M1 - M5
4
Q
which types of muscarinic subtypes are found in peripipheral autonomic tissues?
A
M2 and M3
5
Q
where are M1 and M4 found
A
more abundant in brain and autonomic ganglia
6
Q
what does M1, M3 and M5 interact with
A
Gq proteins
7
Q
what do M2 and M4 receptors interact with to inhibit adenylyl cyclase
A
Gi proteins
8
Q
are most agonists for muscarine receptors selective for subtypes
A
no
