sarcoma de Ewing Flashcards

1
Q

sarcoma de Ewing ese da en

A

px 5-25a

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2
Q

sarcoma de ewing es la neoplasia

A

segunda mas frecuente pediatrica

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3
Q

alteración molecular de sarcoma de Ewing es

A

EWS y ETS

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4
Q

cscs de sarcoma de Ewing es

A

dolor, fiebre, perdida de peso, leucocitosis y sedimentación eritrocitaria elevada
SX SISTEMICOS

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5
Q

rx sarcoma de Ewing se ve como

A

imagen en tela de cebolla

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6
Q

en histologia sarcoma de Ewing se ve como

A

forma de rosetas
células pequeñas y azules

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7
Q

sarcoma Ewing es positivo a IHQ

A

vimentina, CK y NKX2

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8
Q

sarcoma Ewing es negativo IHQ

A

miogenina, CD45, MyoD1 y cromogrsnina

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9
Q

biologia molecular de Ewing es

A

EWSR1/FLI-1
t(11:22)}(q24q12)

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10
Q

factores pronósticos favorables son

A

<10 años
extremidad distal y proximal
<8cm tumor
estadio de dx

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11
Q

factores pronósticos desfavorables son

A

> 18a
pelvis
8cm tumor
estadio de dx

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12
Q

tumor óseo maligno mas frecuente en adulto es

A

metastasis de carcinoma (pulmon, prostata y mama)

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13
Q

tumor óseo maligno primario mas frecuente es

A

mielo multiple

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14
Q

tumor óseo maligno primario mas frecuente despues del mieloma es

A

oteosarcoma

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