cancer de colon Flashcards

1
Q

cancer de colon se da en

A

hombres de 60-70 años

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2
Q

cancer de colon se asocia a

A

bajo consumo de fibras vegetales
alto consumo de grasas

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3
Q

los AINES inhiben COX-2 por lo tanto

A

disminuyen la inflamación

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4
Q

el 80% de carcinoma esporádico es

A

asociado a APC-B catenina que es activado por KRAS

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5
Q

la inestabilidad de microsatelites se da por

A

BRAF/MLH1
(mutilan cosas que no deben de metilar)

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6
Q

los tumores de cancer de colon son

A

proximales y distales

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7
Q

los tumores proximales son

A

exofitico, no obstruye, anemia, sangre oculta en heces

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8
Q

los tumores distales son

A

estenosis , anemia , obstructivo
heces en forma de agujeta
delgadas y aplastadas
rx o tac con contraste muestra mordida de manzana

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9
Q

el pronostico de cancer de colon es

A

profundidad de infiltración y metastasis ganglionares

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10
Q

la infiltración es invasiva

A

infiltración a muscular propia- difícil tx

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11
Q

la infiltración es superficial es

A

infiltración hasta mucosa
buen tx

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12
Q

T de TNM

A

T1- invasion submucosa
T2-invasion muscular propia
T3-invasion hasta serosa
T4-invade otros órganos

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13
Q

N de TNM

A

NX- ganglios regionales no se pueden evaluar
N0- no metastasis a nodules
N1- uno a tres nódulos
N2-cuatro o mas nódulos
N3- nódulos lejanos

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14
Q

M de TNM

A

MX - no se puede observar metastasis
M0-no metastasis a distancia
M1-metastasis a distancia

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