Rheumatology 4

Question 1

Polyarteritis nodosa?

Answer 1

systemic vasculitis

Viral features / Hepatitis

medium sized vasculitides
> aneurysm formation
>

perinuclear antineutrphil cytoplasmic antibodies

Question 2

Behcets is a type?

Answer 2

type 3 hypersensitivity
immune complex deposition

Question 3

syphylis presents?

Answer 3

solitary
small firm

painless genital chancre

Question 4

type 2 herpes simplex virus ulcers?

Answer 4

painful ulcers and vesicles associated with erythema and swelling

Question 5

drug induced lupus abs?

Answer 5

anti-histone antibodies

Question 6

type IV hypersensitivity reaction

Answer 6

allergic contact dermatitis
delayed type

T cell mediated

allergic contact dermatitis

Question 7

type 2 reaction?

Answer 7

IgG
IgM

goodpasture / rheumatic fever/ haemolytic anaemia

Question 8

which TB drug can cause drug induced lupus?

Answer 8

isoniazid

Question 9

Rifampicin?

Answer 9

CYP450 inducer

stain secretiin > orange / red colour

Question 10

Isoniazid

Answer 10

cyp 450 inhibitor

drug induced lupus and peripheral neuropathy

Question 11

interferon alpha adverse effects?

Answer 11

flu like symptoms

Question 12

Stills disease

Answer 12

swinging fever and joint involvement and salmon pink rash