Rheumatology

Question 1

what is alports syndrome?

Answer 1

genetic condition caused by defective productio of type IV collagen

> glomerulonephritis
end stage CKD
heraing loss

Question 2

when should you prescribe allopurinol for gout?

Answer 2

after first attack

Question 3

SLE flare?

Answer 3

ESR is raised but CRP normal

complement levels are deranged

Question 4

moderate / severe psoriatic arthropathy mx?

Answer 4

methotrexate

Question 5

what monoclonal antibodies for psoriatic arthrtitis?

Answer 5

ustekinumab
IL12 IL23

secukinamb
IL-17

Question 6

features of RA on xray?

Answer 6

justa artciular osteopenia

Question 7

Mx GCA?

Answer 7

urgent high dose pred
OR if eye involvement then do
IV methylprednisalone

opthalmology review (risk of vision loss)

Question 8

anterior ischaemic optic neuropathy
fundoscopy findings?

Answer 8

swollen pale disc
blurred margins

Question 9

cherry red spot
pale retina
fundoscopy findings?

Answer 9

ischaemia to the retina

Question 10

schobers test < ?

is indicative of ank spon?

Answer 10

<5.0 cm

Question 11

distance between the two point should not be more than ?

and if increases less than?

Answer 11

20cm in total

<5cm increase

Question 12

step wise mx of ankylosing spondylitis?

Answer 12

oral NSAIDs

second line: tnf alpha blockers
> infliximab / etanercept

Question 13

when can you immediately start alendronate?

Answer 13

> 75 years
fragility fracture

wo dexa scan

Question 14

anti phospholipid

Answer 14

anti-cardiolipin

Question 15

long term s/e of hydroxychlorquinine

Answer 15

retinopathy

Question 16

marfans syndrome

Answer 16

pectus excavatum
pes planus

autosomal dominat
scoliosis >20

mitral valve prolapse

Question 17

onion skin appearnace on XR and lytic lesions of femur?

Answer 17

ewings sarcoma

Question 18

sulfasalazine

Answer 18

IgE mediated allergic reaction

aspirin

Question 19

oligospermia is associated with which commonly prescribed rheum drug?

Answer 19

sulfasaline

Question 20

sjogrens abs?

Answer 20

anti-Ro

Question 21

limited systemic scelrosis ab

Answer 21

anti centromere

Question 22

diffuse cutaneous systemic sclerosis
antibodies

Answer 22

ant0 scl-70

Question 23

raynauds mx?

Answer 23

nifedipine