Oncology

Question 1

SVC obstruction management

Answer 1

oncological emergency

Endovascular stent
Desmopressin

Question 2

most common cause of SVCO?

Answer 2

small cell lung cancer

Question 3

what type of lesions (bone) seen in MM?

Answer 3

osteolytic

Question 4

most common tumour metastases - bone

Answer 4

prostate
breast
lung

Question 5

SCC mx?

Answer 5

8mg oral dexamethasone

Question 6

calcitonin is a marker for?

Answer 6

medullary thyroid cancer

Question 7

which HPV viruses are

Answer 7

HPV 6 and 11

Question 8

hartmans procedure?

Answer 8

sigmoid colectomy and end colostomy

Question 9

RF endometrial cancer?

Answer 9

nulliparous
early menarche
late menopause
unopposed oestrogen

Question 10

Gastrografin enema?

Answer 10

passing water soluble radiopaque liquid into rectum

> radiographs

to assess leaks in colrectal anstomosis

Question 11

CLL can transform into?

Answer 11

High grade lymphoma

Question 12

flutamide?

Answer 12

anti androgen synthetic

Question 13

post op analgeisa
> epidural?

Answer 13

faster return of normal bowel function

Question 14

Mx of suspected neoplastic spinal cord compression?

Answer 14

immediate dose dexamethasone
arrange urgent hospital admission

Question 15

burkitts gene?

Answer 15

c-myc gene translocation

Question 16

which type of hodgkins has worse prognosis?

Answer 16

lymphocyte depleted

Question 17

cLL

Answer 17

hypogammaglublinaemia
> recurrent infcetion

smear cells
warm autoimmune haemolytic anaemia

Question 18

tumour marker in breast cancer?

Answer 18

ca15-3

Question 19

raised AFP and b-HCG which type of testicular cancer?

Answer 19

non seminomatous testicular cancer

Question 20

cytotoxic drugs

causes peripheral neuropathy?

Answer 20

vincristine

Question 21

cardiomyopathy is a s/e of which cytotoxic drug? doxorubicin

Answer 21

doxorubicin

Question 22

cytotoxic drugs
lung fibrosis
/ pulmonary fibrosis

Answer 22

Bleomycin

Question 23

Doxorubicin

S/E

Answer 23

cardiomegaly / cardiotoxic

Question 24

cyclophosphamide affects?

Answer 24

bladder

myelosuppression

Question 25

what acts on microtubules and adverse effects include

> peripheral neuropathy?

Answer 25

Vincristine

Question 26

what is an anthracycline?

Answer 26

Doxorubicin

stabilizes DNA tropoisomerase II complex inhibitor

Question 27

Nausea chemotherapy induced

management?

Answer 27

ondansetron 5HT-3 receptor antagonist

Question 28

metoclopramide would be useful?

Answer 28

promoting bowel motility
D2- anatgonist

Question 29

how does ondansetron work?

Answer 29

Blocks action of serotonin
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