Gastro 3

Question 1

Diarrhoea defn:

Answer 1

> 3 loose /watery stools per day

Question 2

acute diarrhoea?

Answer 2

<14 days

Question 3

IBS features

Answer 3

abdominal pain
bloating
change in bowel habit

Question 4

In pts taking aminosalicylates

presenting with sore throat what is really important to rule out?

Answer 4

agranulocytosis
> FBC check

Question 5

relapse of UC what drugs to maintain remission?

Answer 5

oral AZATHIOPURINE
MERCAPTOPURINE

Question 6

Urinary 5-hydroxyindoleacetic acid is used for?

Answer 6

carcinoid tumours

Question 7

oesophageal variceal bleed mx

Answer 7

endoscopic band ligation
> band constrict varices
> shrink and fall out

Question 8

Injection sclerotherapy
mx for?

Answer 8

kinda second line
gastric varices
> butyl cyanoacrylate

Question 9

loperamide MOA

Answer 9

u-opiod receptor agonist

reduction of peristalsis
= decreased gastric motility

Question 10

Crohns inducing remission?

Answer 10

glucocorticoids

> Budesonide alternative

2)AZA/mercaptopurine
3) ubfliximab

Question 11

acute mesenteric ischaemia
first line investigation?

Answer 11

serum lactate

lack of blood supply causing anaerobic metabolism
lactic acid production

Question 12

PPIs can increase the risk of?

Answer 12

osteoporosis and fractures

malabsorption of calciuma ndmagnesium

Question 13

Most valuable investigation for someone presenting w cholesatitic picture

Answer 13

USS of abdomen - gallstone or not

Question 14

which abx can cause cholestasis?

Answer 14

Co-amoxiclav is a well recognised cause of cholestasis

Question 15

Hypogonadotrophic hypogonadism

Answer 15

FSH /LH low
anterior pituitary gland not releasing it

• oestrogen / testosterone / progesterone low

Question 16

maddreys discriminant includes which two things?

Answer 16

prothrombin time
serum bilirubin

Question 17

suspected perforated peptic ulcer

most appropriate step?

Answer 17

erect cxr

Question 18

known peptic ulcer
what things are suggestive of perforation?

Answer 18

acute presentation
abdo pain
peritonism

Question 19

PPI should be stopped how long before upper GI endoscopy?

Answer 19

2 weeksa

Question 20

severe flare up of UC
what investigation?

Answer 20

sigmoidoscopy

Question 21

what is the double duct signs on MRCP?

Answer 21

dilatation of both common bile duct
and pancreatic duct

> head of pancreas cancer

Question 22

hoarseness in oesophageal carcinoma?

Answer 22

laryngeal nerve damage

Question 23

13C urea breath test

which drugs affect?

Answer 23

no abx in 4 weeks
no PPI in 2 weeks