Rheumatology Flashcards
What is Rheumatoid factor?
An IgM against IgG Fc
What are Tophi?
Gout crystals & giant cells
What is Podagra?
Big toe inflammation from gout
What is CREST syndrome?
Calcinosis cutis
Raynaud’s phenomenon
Esophageal dysmotility
Sclerodactyly
Telangiectasias
What Ab is associated with CREST?
Anti-centromere Ab
What diseases have Raynaud’s syndrome?
Scleroderma
Takayasu’s
RA
SLE
What platelet count do most types of vasculitis have?
Low platelets
Which vasculitis has a high platelet count?
Kawasaki disease
Which vasculitis has a normal platelet count?
Henoch-Schönlein Purpura
What is Osteoarthritis?
Pain worse w/ activity
PIP/DIP joints affected
What is Rheumatoid Arthritis?
Pain worse in the morning
MCP/PIP joints affected
What is Stills’ disease?
Juvenile RA
What is Pseudogout?
Pyrophosphate crystals in knees/wrists
What is gout?
Urate crystals in big toe
(-) birefringence
What is myositis?
1 muscle hurts
What is polymyositis?
> 1 muscle hurts
What is dermatomyositis?
Myositis & rash
What is fibromyalgia?
Hurt all the time, 11 trigger points
What is Polymyalgia rheumatica?
Weak shoulder or pelvic girdle
Temporal arteritis
What is SLE = Lupus?
Meet 4 criteria: “DOPAMIN RASH”
- discoid rash
- oral ulcers
- photosensitivity
- arthritis
- malar rash
- immunologic disorder (Ab: anti-dsDNA, anti-Smith, anti-cardiolipin)
- neurological disorder (seizures or psychosis)
- renal failure (cause of death)
- ANA
- serositis: pleuritis/pericarditis (Libman-Sacks endocarditis)
- hemolytic anemia
What is scleroderma?
Tight skin
Fibrosis
What is Takayasu’s arteritis?
Pulseless Asian women
Aorta inflammation (=> granuloma)
What is polyarteritis nodosa?
Ab: p-ANCA
Attacks gut/kidney
Hep B
What is Wegener’s granulomatosis?
Ab: c-ANCA
Attacks ENT, lungs, kidney
What is Goodpasture’s?
Ab: anti-GBM
Attacks lung/kidney
type of RPGN
What is Reiter’s syndrome?
Males that can’t see, pee, or climb a tree
What is Sjögren’s syndrome?
Females that have dry eyes/mouth
Subtype of RA
What is Behçet’s syndrome?
Oral and genital ulcers
Uveitis
What is Churg-Strauss?
Asthma in young adult
Eosinophils
Multi-organ involved
What is Felty’s syndrome?
Subtype of RA
W/ leukopenia and splenomegaly
What is Kawasaki’s disease?
CRASH
- conjunctivitis
- rash (palm/sole)
- aneurysm (coronary artery) => MI in kids
- strawberry tongue
- hot (= fever > 102F for at least 3 days & cervical lymphadenopathy)
