Muscle Flashcards

1
Q

Where is CK-MB found?

A

Heart

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2
Q

Where is CK-MM found?

A

Muscle

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3
Q

Where is CK-BB found?

A

Brain

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4
Q

Why should you wait 30 min after a meal before swimming?

A

All blood in gut and skeletal mm have ran out of ATP

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5
Q

How does a neurogenic muscle disease present?

A

Distal weakness & fasciculations

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6
Q

How does a myopathic muscle disease present?

A

Proximal weakness & pain

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7
Q

What is a light chain composed of?

A

Actin

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8
Q

What is a heavy chain composed of?

A

Myosin

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9
Q

What band of the sarcomere does not change length?

A

A-band

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10
Q

Where are the T-tubules located?

A

Cardiac muscle: Z line
Skeletal muscle: A-band junction with I-band

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11
Q

What is Duchenne’s MD?

A

Dystrophin mutation
Frameshift mutation
Gower’s sign
Calf pseudohypertrophy

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12
Q

What is Becker’s MD?

A

Dystrophin mutation
Missense mutation
Sx >5y

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13
Q

What is myotonic dystrophy?

A

Bird’s beak face
Cannot let go when shaking hands

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14
Q

What is myasthenia syndrome (= Lambert-Eaton)?

A

Gets stronger as day goes by
Stronger w/ EMG
Not associated w/ small cell carcinoma

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15
Q

What is Myasthenia gravis?

A

Gets weaker as day goes on
Stronger w/ edrophonium
Weaker w/ EMG
Rule out thymoma

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16
Q

What is multiple sclerosis?

A

Anti-myelin Ab
Young woman w/ vision problems
Sx come and go

17
Q

What is metachromatic leukodystrophy?

A

Arylsulfatase deficiency
Kid w/ MS presentation

18
Q

What is Ataxia Telangiectasia?

A

Spider veins
d/t IgA deficiency

19
Q

What is Friedrich’s ataxia?

A

Retinitis pigmentosa
Scoliosis

20
Q

What is Adrenal Leukodystrophy?

A

Carnitine shuttle problem
Adrenal failure

21
Q

What is Guillain-Barre?

A

Ascending paralysis
2 weeks after URI

22
Q

What is ALS?

A

Middle age male w/ fasciculations
Descending paralysis
No sensory problems

23
Q

What is Werdnig-Hoffman?

A

Fasciculations in a newborn
No anterior horns

24
Q

What is Polio?

A

Asymmetric fasciculations in child
2 weeks after gastroenteritis

25
Q

What is choreoathetosis?

A

Dance-like movements
Wringing of hands
Quivering voice

26
Q

What is atonic cerebral palsy?

A

No muscle tone
Floppy