Pharmacology Flashcards

1
Q

What drugs act as haptens on platelets?

A

Aspirin
Heparin
Quinidine

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2
Q

What drugs act as haptens on RBCs?

A

PAD PACS
- Penicillamine
- alpha-methyldopa
- Dapsone

  • PTU
  • Antimalarials
  • Cephalosporins
  • Sulfa drugs
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3
Q

What drugs wipe out the bone marrow?

A

ABCV
- AZT
- Benzene
- Chloramphenicol
- Vinblastine

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4
Q

What drugs wipe out granulocytes?

A

Carbamazepine
Clozapine
Ticlopidine

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5
Q

What drugs cause pulmonary fibrosis?

A

My Tiny Nose Cannot Breathe Bad Air
- Methotrexate
- Tocainide
- Nitrofurantoin
- Carmustine
- Bleomycin
- Busulfan
- Amiodarone

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6
Q

What drugs dilate veins and arteries?

A

ACE inhibitors
Nitrates

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7
Q

What are the anti-inflammatory actions of steroids?

A

I KISS
- inhibits PLP-A
- Kills T cells and eosinophils
- inhibits macrophage migration
- stabilizes mast cells
- stabilizes endothelium

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8
Q

What do opioid mu receptors cause?

A

Mental side effects

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9
Q

What do opioid kappa receptors cause?

A

Pain relief

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10
Q

What drugs have sulfur in them?

A

ACE inhibitors
Celecoxib
Loop diuretics
Thiazides
Sulfonylureas
Sulfonamides

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11
Q

What are the short-acting DM Type 1 drugs?

A

Lispro
Regular
Asparte

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12
Q

What are the intermediate-acting DM Type 1 drugs?

A

NPH
Lente

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13
Q

What are the long-acting DM Type 1 drugs?

A

Glargine
Ultralente

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14
Q

What drugs cause SLE?

A

HIPPPE
- Hydralazine
- INH
- Procainamide
- Phenytoin
- Penicillamine
- Ethosuximide

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15
Q

What antibody is associated with drug-induced lupus?

A

Anti-histone Ab

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16
Q

What drugs cause labor induction?

A

PGE2 -> ripens cervix
Oxytocin -> increase contractions
Pitocin -> increase contractions

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17
Q

What drugs cause labor halt (= tocolytics)?

A

Hydration (stop ADH = oxytocin)
MgSO4 -> decrease contractions
Terbutaline -> decrease contractions
Ritodrine -> incr edema, decr contractions

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18
Q

What drugs can be nephrotoxic?

A

Water-soluble drugs

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19
Q

What drugs can be hepatotoxic?

A

Fat-soluble drugs

20
Q

How do you treat acetaminophen overdose?

A

N-acetylcysteine

21
Q

How do you treat Benzodiazepine overdose?

A

Flumazenil

22
Q

How do you treat ß-blocker overdose?

23
Q

How do you treat CCB overdose?

A

Calcium chloride + glucagon

24
Q

How do you treat CO poisoning?

25
Q

How do you treat Cu, Gold, Cd, Mercury, Arsenic poisoning?

A

Penicillamine

26
Q

How do you treat cyanide poisoning?

A

Amyl nitrite

27
Q

How do you treat ethylene glycol, MeOH overdose?

A

EtOH
Fomepizole

28
Q

How do you treat Fe overdose?

A

Deferoxamine

29
Q

How do you treat fibrinolytic overdose?

A

Aminocaproic acid

30
Q

How do you treat heparin overdose?

A

Protamine sulfate

31
Q

How do you treat Lithium overdose?

A

Sodium polystyrene sulfonate

32
Q

How do you treat Nitrite overdose?

A

Methylene blue

33
Q

How do you treat organophosphate poisoning?

A

Atropine + Pralidoxime

34
Q

How do you treat opioid overdose?

35
Q

How do you treat Pb poisoning?

36
Q

How do you treat salicylate overdose?

A

Charcoal or bicarbonate

37
Q

How do you treat TCA overdose?

A

Bicarbonate
(Prevent arrhythmias)

38
Q

How do you treat Theophylline overdose?

39
Q

How do you treat Warfarin overdose?

40
Q

What drugs causes myositis?

A

RIPS
- Rifampin
- INH
- Prednisone
- Statins

41
Q

What drugs cause disulfiram reactions?

A

Metronidazole
Cephalosporins
Procarbazine

42
Q

What drugs cause dysgeusia?

A

Metronidazole
Clarithromycin
Lithium

43
Q

What antibiotics are in a triple antibiotic ointment?

A

“Brand New Potion”
- Bacitracin
- Neomycin
- Polymyxin D

44
Q

What is the 1-dose treatment for Chlamydia?

A

Azithromycin

45
Q

What are the 1-dose treatments for Gonorrhea?

A

“TRI to FIX the FOX w/ cephalosporins”
- cefTRIaxone
- ceFIXime
- ceFOXitin

46
Q

What bugs are treated with vancomycin?

A

MRSA
Staph. epidermidis
Enterococcus

47
Q

What is the treatment for malaria?

A

Quinine (tinnitus)
Mefloquine (good liver penetration)
Primaquine (prevents relapse, high bug resistance)
Chloroquine (kills RBCs)