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Pharmacology Flashcards

1
Q

What drugs act as haptens on platelets?

A

Aspirin
Heparin
Quinidine

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2
Q

What drugs act as haptens on RBCs?

A

PAD PACS
- Penicillamine
- alpha-methyldopa
- Dapsone

  • PTU
  • Antimalarials
  • Cephalosporins
  • Sulfa drugs
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3
Q

What drugs wipe out the bone marrow?

A

ABCV
- AZT
- Benzene
- Chloramphenicol
- Vinblastine

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4
Q

What drugs wipe out granulocytes?

A

Carbamazepine
Clozapine
Ticlopidine

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5
Q

What drugs cause pulmonary fibrosis?

A

My Tiny Nose Cannot Breathe Bad Air
- Methotrexate
- Tocainide
- Nitrofurantoin
- Carmustine
- Bleomycin
- Busulfan
- Amiodarone

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6
Q

What drugs dilate veins and arteries?

A

ACE inhibitors
Nitrates

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7
Q

What are the anti-inflammatory actions of steroids?

A

I KISS
- inhibits PLP-A
- Kills T cells and eosinophils
- inhibits macrophage migration
- stabilizes mast cells
- stabilizes endothelium

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8
Q

What do opioid mu receptors cause?

A

Mental side effects

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9
Q

What do opioid kappa receptors cause?

A

Pain relief

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10
Q

What drugs have sulfur in them?

A

ACE inhibitors
Celecoxib
Loop diuretics
Thiazides
Sulfonylureas
Sulfonamides

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11
Q

What are the short-acting DM Type 1 drugs?

A

Lispro
Regular
Asparte

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12
Q

What are the intermediate-acting DM Type 1 drugs?

A

NPH
Lente

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13
Q

What are the long-acting DM Type 1 drugs?

A

Glargine
Ultralente

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14
Q

What drugs cause SLE?

A

HIPPPE
- Hydralazine
- INH
- Procainamide
- Phenytoin
- Penicillamine
- Ethosuximide

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15
Q

What antibody is associated with drug-induced lupus?

A

Anti-histone Ab

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16
Q

What drugs cause labor induction?

A

PGE2 -> ripens cervix
Oxytocin -> increase contractions
Pitocin -> increase contractions

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17
Q

What drugs cause labor halt (= tocolytics)?

A

Hydration (stop ADH = oxytocin)
MgSO4 -> decrease contractions
Terbutaline -> decrease contractions
Ritodrine -> incr edema, decr contractions

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18
Q

What drugs can be nephrotoxic?

A

Water-soluble drugs

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19
Q

What drugs can be hepatotoxic?

A

Fat-soluble drugs

20
Q

How do you treat acetaminophen overdose?

A

N-acetylcysteine

21
Q

How do you treat Benzodiazepine overdose?

A

Flumazenil

22
Q

How do you treat ß-blocker overdose?

23
Q

How do you treat CCB overdose?

A

Calcium chloride + glucagon

24
Q

How do you treat CO poisoning?

25
How do you treat Cu, Gold, Cd, Mercury, Arsenic poisoning?
Penicillamine
26
How do you treat cyanide poisoning?
Amyl nitrite
27
How do you treat ethylene glycol, MeOH overdose?
EtOH Fomepizole
28
How do you treat Fe overdose?
Deferoxamine
29
How do you treat fibrinolytic overdose?
Aminocaproic acid
30
How do you treat heparin overdose?
Protamine sulfate
31
How do you treat Lithium overdose?
Sodium polystyrene sulfonate
32
How do you treat Nitrite overdose?
Methylene blue
33
How do you treat organophosphate poisoning?
Atropine + Pralidoxime
34
How do you treat opioid overdose?
Naloxone
35
How do you treat Pb poisoning?
Succimer
36
How do you treat salicylate overdose?
Charcoal or bicarbonate
37
How do you treat TCA overdose?
Bicarbonate (Prevent arrhythmias)
38
How do you treat Theophylline overdose?
Esmolol
39
How do you treat Warfarin overdose?
Vit K
40
What drugs causes myositis?
RIPS - Rifampin - INH - Prednisone - Statins
41
What drugs cause disulfiram reactions?
Metronidazole Cephalosporins Procarbazine
42
What drugs cause dysgeusia?
Metronidazole Clarithromycin Lithium
43
What antibiotics are in a triple antibiotic ointment?
“Brand New Potion” - Bacitracin - Neomycin - Polymyxin D
44
What is the 1-dose treatment for Chlamydia?
Azithromycin
45
What are the 1-dose treatments for Gonorrhea?
“TRI to FIX the FOX w/ cephalosporins” - cefTRIaxone - ceFIXime - ceFOXitin
46
What bugs are treated with vancomycin?
MRSA Staph. epidermidis Enterococcus
47
What is the treatment for malaria?
Quinine (tinnitus) Mefloquine (good liver penetration) Primaquine (prevents relapse, high bug resistance) Chloroquine (kills RBCs)

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