Pharmacology Flashcards
What drugs act as haptens on platelets?
Aspirin
Heparin
Quinidine
What drugs act as haptens on RBCs?
PAD PACS
- Penicillamine
- alpha-methyldopa
- Dapsone
- PTU
- Antimalarials
- Cephalosporins
- Sulfa drugs
What drugs wipe out the bone marrow?
ABCV
- AZT
- Benzene
- Chloramphenicol
- Vinblastine
What drugs wipe out granulocytes?
Carbamazepine
Clozapine
Ticlopidine
What drugs cause pulmonary fibrosis?
My Tiny Nose Cannot Breathe Bad Air
- Methotrexate
- Tocainide
- Nitrofurantoin
- Carmustine
- Bleomycin
- Busulfan
- Amiodarone
What drugs dilate veins and arteries?
ACE inhibitors
Nitrates
What are the anti-inflammatory actions of steroids?
I KISS
- inhibits PLP-A
- Kills T cells and eosinophils
- inhibits macrophage migration
- stabilizes mast cells
- stabilizes endothelium
What do opioid mu receptors cause?
Mental side effects
What do opioid kappa receptors cause?
Pain relief
What drugs have sulfur in them?
ACE inhibitors
Celecoxib
Loop diuretics
Thiazides
Sulfonylureas
Sulfonamides
What are the short-acting DM Type 1 drugs?
Lispro
Regular
Asparte
What are the intermediate-acting DM Type 1 drugs?
NPH
Lente
What are the long-acting DM Type 1 drugs?
Glargine
Ultralente
What drugs cause SLE?
HIPPPE
- Hydralazine
- INH
- Procainamide
- Phenytoin
- Penicillamine
- Ethosuximide
What antibody is associated with drug-induced lupus?
Anti-histone Ab
What drugs cause labor induction?
PGE2 -> ripens cervix
Oxytocin -> increase contractions
Pitocin -> increase contractions
What drugs cause labor halt (= tocolytics)?
Hydration (stop ADH = oxytocin)
MgSO4 -> decrease contractions
Terbutaline -> decrease contractions
Ritodrine -> incr edema, decr contractions
What drugs can be nephrotoxic?
Water-soluble drugs
What drugs can be hepatotoxic?
Fat-soluble drugs
How do you treat acetaminophen overdose?
N-acetylcysteine
How do you treat Benzodiazepine overdose?
Flumazenil
How do you treat ß-blocker overdose?
Glucagon
How do you treat CCB overdose?
Calcium chloride + glucagon
How do you treat CO poisoning?
100% O2
How do you treat Cu, Gold, Cd, Mercury, Arsenic poisoning?
Penicillamine
How do you treat cyanide poisoning?
Amyl nitrite
How do you treat ethylene glycol, MeOH overdose?
EtOH
Fomepizole
How do you treat Fe overdose?
Deferoxamine
How do you treat fibrinolytic overdose?
Aminocaproic acid
How do you treat heparin overdose?
Protamine sulfate
How do you treat Lithium overdose?
Sodium polystyrene sulfonate
How do you treat Nitrite overdose?
Methylene blue
How do you treat organophosphate poisoning?
Atropine + Pralidoxime
How do you treat opioid overdose?
Naloxone
How do you treat Pb poisoning?
Succimer
How do you treat salicylate overdose?
Charcoal or bicarbonate
How do you treat TCA overdose?
Bicarbonate
(Prevent arrhythmias)
How do you treat Theophylline overdose?
Esmolol
How do you treat Warfarin overdose?
Vit K
What drugs causes myositis?
RIPS
- Rifampin
- INH
- Prednisone
- Statins
What drugs cause disulfiram reactions?
Metronidazole
Cephalosporins
Procarbazine
What drugs cause dysgeusia?
Metronidazole
Clarithromycin
Lithium
What antibiotics are in a triple antibiotic ointment?
“Brand New Potion”
- Bacitracin
- Neomycin
- Polymyxin D
What is the 1-dose treatment for Chlamydia?
Azithromycin
What are the 1-dose treatments for Gonorrhea?
“TRI to FIX the FOX w/ cephalosporins”
- cefTRIaxone
- ceFIXime
- ceFOXitin
What bugs are treated with vancomycin?
MRSA
Staph. epidermidis
Enterococcus
What is the treatment for malaria?
Quinine (tinnitus)
Mefloquine (good liver penetration)
Primaquine (prevents relapse, high bug resistance)
Chloroquine (kills RBCs)