Neurology Flashcards

1
Q

What is the central nervous system?

A

Brain
Spinal cord
Oligodendrocytes

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2
Q

What is the peripheral nervous system?

A

Everything other than Brain and Spinal cord
Schwann cells

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3
Q

What is the autonomic nervous system?

A

Automatic stuff

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4
Q

What is the somatic nervous system?

A

Moving your muscles

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5
Q

What is the parasympathetic system?

A

Rest-and-Digest

(=> slows stuff down)

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6
Q

How does the parasympathetic system behave?

A

DUMBBELS

Diarrhea
Urination
Miosis “constrict”
Bradycardia
Bronchoconstrict
Erection “point”
Lacrimation
Salivation

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7
Q

What is the sympathetic system?

A

Fight-or-Flight

(=> speeds stuff up)

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8
Q

How does the sympathetic system behave?

A

Opposite of Parasympathetics

Constipation
Urinary retention
Mydriasis “eyes wide with fright”
Tachycardia
Bronchodilate
Ejaculation “shoot”
Xerophthalmia (dry eyes)
Xerostomia (dry mouth)

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9
Q

Where is NE synthesized?

A

Locus cerulean of the pons

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10
Q

What happens to NE in anxiety?

A

Goes up

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11
Q

What happens to NE in depression?

A

Goes down

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12
Q

Where is dopamine synthesized?

A

Ventral tegmentum and SNc in the midbrain

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13
Q

What happens to dopamine in Huntington’s?

A

Goes up

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14
Q

What happens to dopamine in Parkinson’s and depression?

A

Goes down

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15
Q

Where is serotonin synthesized?

A

Raphe nucleus

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16
Q

What happens to serotonin in Parkinson’s?

A

Goes up

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17
Q

What happens to serotonin in anxiety and depression?

A

Goes down

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18
Q

Where is ACh synthesized?

A

Basal nucleus of Meynert

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19
Q

What happens to ACh in Parkinson’s?

A

Goes up

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20
Q

What happens to ACh in Alzheimer’s and Huntington’s?

A

Goes down

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21
Q

What does the forebrain or prosencephalon give rise to?

A

Telencephalon -> Cerebral Hemispheres
Diencephalon -> Thalamus

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22
Q

What does the midbrain or mesencephalon give rise to?

A

Mesencephalon -> midbrain

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23
Q

What does the hindbrain or rhombencephalon give rise to?

A

Metencephalon -> pons and cerebellum
Myelencephalon -> medulla

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24
Q

What is Cushing’s triad?

A

HTN
Bradycardia
Elevated ICP

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25
What is Budd-Chiari?
Hepatic vein obstruction
26
What is anencephaly?
Notochord did not make contact w/ brain => only have medulla
27
What is an Encephalocele?
Brain tissue herniation
28
What is a Dandy-Walker malformation?
No cerebellum Distended 4th/lateral ventricles
29
What is an Arnold-Chiari malformation?
Herniation of cerebellum through foramen magnum Type I = cerebellar tonsils (asymptomatic) Type II = cerebellar vermis/medulla => hydrocephalus, syringomyelia (loss of pain/temp)
30
What is spina bifida occulta?
Covered by skin w/ tuft of hair
31
What is spina bifida aperta?
Has opening (High AFP)
32
What is a meningocele?
Sacral pocket w/ meninges in it
33
What is a meningomyelocele?
Sacral pocket w/ meninges and nerves in it
34
What is open-angle glaucoma?
Overproduction of fluid - painless ipsilateral dilated pupil - gradual tunnel vision - optic disc cupping
35
What is closed-angle glaucoma?
Obstruction of canal of Schlemm - sudden onset - pain - emergency
36
What are the watershed areas?
Hippocampus Splenic flexure
37
What are the contents of the cavernous sinus?
CN III CN IV CN V1 CN V2 CN VI Postganglionic sympathetic fibers
38
What bug loves the frontal lobe?
Rubella
39
What bug loves the temporal lobe?
HSV
40
What bug loves the parietal lobe?
Toxoplasma
41
What bug loves the hippocampus?
Rabies
42
What bug loves the posterior fossa?
TB = mycobacterium tuberculosis
43
What bug loves the DC/ML tract?
Treponema
44
How do migraines present?
Aura Photophobia Numbness Tingling Throbbing HA Nausea
45
How do tension headaches present?
“Band-like” pain Starts in posterior neck, worse as day progresses, sleep disturbance
46
How do cluster headaches present?
Rhinorrhea Unilateral orbital pain Suicidal Facial flushing Worse w/ lying down
47
How does temporal arteritis present?
Pain with chewing Blind in one eye
48
How does trigeminal neuralgia present?
Sharp, shooting face pain
49
What are 2 kinds of partial seizures?
Simple (aware) Complex (not aware)
50
What are 3 kinds of generalized seizures?
Tonic-Clonic = “grand mal” Absence = “petit mal” Status epilepticus
51
How does an epidural hematoma present?
Intermittent consciousness “Lucid interval”
52
How does an epidural hematoma look on CT?
Biconvex lens (Does not cross suture lens)
53
How does a subdural hematoma present?
Headache 4 wks after trauma Elderly (loose brain)
54
How does a subdural hematoma look on CT?
Crescent-shaped Crosses suture lines Contains midline shift
55
How does a subarachnoid hemorrhage present?
“Worst headache of my life” H/o berry aneurysm
56
What is an astrocytoma?
Rosenthal fibers #1 in kids with occipital mass
57
What is an ependymoma?
Rosettes In 4th ventricle Hydrocephalus
58
What is seen with a craniopharyngioma?
Motor oil biopsy Tooth enamel Rathke’s pouch ADH problem Bitemporal hemianopsia
59
What is associated with Glioblastoma multiforme?
Pseudopalisading Necrosis Worst prognosis Intralesional hemorrhage
60
What is a hemangioblastoma associated with?
Cerebellum Von-Hippel-Lindau’s Blood vessel tumor
61
What is associated with a medulloblastoma?
Pseudorosettes Compresses the brain Early morning vomiting
62
What is associated with a meningioma?
Parasagittal Psammoma bodies Whorling pattern Best prognosis
63
What are the most common places to metastasize to the brain?
From lung, breast, skin See at white-grey matter junction in brain
64
What is associated with an oligodendroglioma?
Fried-egg appearance Nodular calcification
65
What is associated with pinealoma?
Loss of upward gaze Loss of circadian rhythms (=> precocious puberty)
66
What is associated with a schwannoma?
CN VIII tumor Unilateral deafness
67
What is associated with neurofibromatosis?
Cafe au lait spots (hyperpigmentation) => peripheral nerve tumors, axillary freckle Type 1 = Von Recklinghausen’s - peripheral (chr 17) - optic glioma - Lisch nodules - scoliosis Type 2 - “Acoustic neuroma” - central (chr 22) - cataracts - bilateral deafness
68
What is associated with Sturge-Weber?
Port-wine stain (big purple spot) on forehead Angioma of retina
69
What is associated with tuberous sclerosis?
Ash leaf spots (hypopigmentation) Primary brain tumors Heart rhabdomyomas Renal cell carcinoma Shagreen spots (leathery)