Review of GI Anatomy I Flashcards
The elimination of insoluble substances and other materials occurs in the
Large intestine
After the oral cavity, the digestive system consists of which 4 layers?
- ) Mucosa
- ) Submucosa
- ) Muscularis Externa
- ) Serosa/adventitia
Epithelium of the mucosal layer lines the lumen of the digestive tract and originates from ENDODERM for
Forgut, midgut, and hindgut derivatives (pharynx to large intestine)
The things that are derived from ectoderm are derivatives of the
Stomodeum and proctodeum (mouth and lower anal canal)
Forms from invagination of the developing gut epithelium and intramural-extramural glands extend through the gut layers with ducts that carry secretions to the luminal surface
Glandular Epithelium
Surrounds the endoderm and forms connective tissue, muscle, and serosa of the digestive viscera
Mesoderm
Neural crest cells migrate into the gut to form the
Enteric ganglia
By week 4, the primordial gut is made up of endoderm-lined
Foregut, midgut, and hindgut
Forms epithelium of the pharynx, esophagus, stomach, proximal duodenum and liver, gall bladder, pancreas with associated duct systems
Foregut endoderm
Forms epithelium of the distal duodenum, jejunum, ileum, cecum, appendix, ascending colon, proximal ⅔ transverse colon
Midgut endoderm
The midgut is initially connected to the yolk sac via the
Vitteline Duct
Forms epithelium of the distal ⅓ transverse colon, descending colon, sigmoid colon, rectum, proximal part of anal canal
Hindgut endoderm
The ectoderm-endoderm membranes of the stomodeum and foregut form the
Oropharyngeal/buccopharyngeal membrane
A birth defect in which the gut structures remain herniated at the umbilicus because of failure of intestines to return back to abdominal cavity during development
Omphalocele
In omphalocele, are the intestines in contact with the amniotic fluid?
No
Early in development, the embryonic body cavity (intraembryonic coelom) is lined with
Mesoderm
Divides into visceral and parietal mesoderm with an intervening body cavity
Lateral Plate mesoderm
Thus, the body cavity in the abdominopelvic region is the
Peritoneal cavity
Organs that protrude into the peritoneal cavity only slightly are
-Example: kidneys
Retroperitoneal
Others such as the stomach and spleen protrude completely and are
Intraperitoneal
Intraperitoneal organs are connected to the posterior abdominal wall by a
Mesentery
Between the thoracic diaphragm superiorly, pelvic diaphragm inferiorly, abdominal wall anterolaterally, vertebral column-muscles posteriorly
Abdominopelvic cavity
A serosa/serous membrane that covers intraperitoneal organs and peritoneal walls
Peritoneum
Consists of mesothelium (simple squamous epithelium) with a thin layer of supportive loose connective tissue
Serosa
Continuity between parietal and visceral peritoneum occurs in
Mesentery
Double-layered peritoneal membranes that form from continuity between parietal and visceral peritonea passing between the posterior body wall and the viscera
Mesenteries
The hepatoduodenual ligament is a double layer of peritoneum at the free edge of the lesser omentum that connects duodenum to liver. It conducts the
Portal triad (hepatic portal vein, proper hepatic artery, common bile duct)
The parietal peritoneum is supplied by the same neurovasculature as the overlying body wall and is thus sensitive to
Pressure, pain, heat, cold, and laceration
Somatic pain from the parietal peritoneum is generally
Well localized
Patients experience more pain with large incisions of the well-innervated parietal peritoneum. Small laparoscopic incisions reduce pain and potential for contamination and
Peritonitis
Insensitive to touch, heat, cold, and laceration
Visceral peritoneum
Poorly localized visceral pain from the visceral peritoneum is activated by stretching and chemical irritation and is referred to
Dermatomes
Where is pain from the foregut, midgut, and hindgut typically located?
- ) Foregut = epigastric
- ) Midgut = umbilical
- ) Hindgut = hypogastric
Include stomach, liver, gall bladder, spleen, tail of pancreas, beginning of duodenum, jejunum, ileum, cecum, appendix, transverse colon, sigmoid colon
Intraperitoneal organs
Include most of duodenum, ascending colon, descending colon, most of pancreas, upper rectum
Secondarily retroperitoneal organs
Include kidney, adrenal gland, ureter, aorta, IVC, lower rectum, anal canal
Primary retroperitoneal organs
Inflamed peritoneum (from surgery or infection) can lead to surfaces that are sticky with
Fibrin
During healing, fibrous scar tissue can form abnormal attachments between visceral and parietal serosal layers, known as
Adhesions
This tethering may cause chronic pain or emergency complications such as
Intestinal obstruction
The arterial supply to the structures of the oral cavity, pharynx, and upper esophagus are from
Branches of external carotid and subclavian arteries, and the thoracic aorta