Gastrointestinal Physiology: Secretion II Flashcards
Where is the Na+ concentration higher, in the gall bladder bile or in the liver bile?
Gall bladder bile
As the volume of bile increases in the gallbladder, the smooth muscle stretches with little increase in wall tension until we reach a
Critical volume
At this volume, the wall tension rapidly increases and rhythmic contractions start, leading to
Gall bladder emptying
Flows out of the liver, through the common bile duct and into the gallbladder or duodenum in response to the secretion pressure developed in the blind end of the biliary tract
Bile
Secretion at the hepatocyte can produce a hydrostatic pressure within the canaliculi of
10-20mmHg
The newly formed bile follows the path of least resistance into either the
Gall bladder or duodenum
During the interdigestive period, most of the bile flows into the gallbladder due to higher muscle tone in the lower common bile duct and the
Sphincter of Oddi
Upon eating, increasing amounts of bile flow directly into the duodenum because the muscle tone of the gallbladder increases while that of the lower common bile duct and sphincter of Oddi
Decreases